15216


Mus musculus (NCBI)

Features
Gene ID: 15216
  
Biological name :
  
Synonyms : hemochromatosis / Hfe / MR2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422645_at (Mouse Genome 430 2.0 Array)   1450702_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_011242586.1
RefSeq - 31981697
RefSeq - 568981570
RefSeq - 568981572
RefSeq - 755544110
RefSeq - NC_000079.6
RefSeq - NP_001334422.1
RefSeq - NP_034554.2
RefSeq - XP_006516619.1
RefSeq - XP_006516620.1
RefSeq - 1108846823
RefSeq - NM_001347493.1
RefSeq - NM_010424.5
RefSeq - XM_006516557.3
RefSeq - XM_011244284.2
RefSeq - XM_006516556.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000006611 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001913 T cell mediated cytotoxicity IBA
 biological_processGO:0002626 negative regulation of T cell antigen processing and presentation IEA
 biological_processGO:0002725 negative regulation of T cell cytokine production ISO
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0010039 response to iron ion ISO
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ISO
 biological_processGO:0030101 natural killer cell activation IBA
 biological_processGO:0030509 BMP signaling pathway ISO
 biological_processGO:0032092 positive regulation of protein binding ISO
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IC
 biological_processGO:0042267 natural killer cell mediated cytotoxicity IBA
 biological_processGO:0042271 susceptibility to natural killer cell mediated cytotoxicity IBA
 biological_processGO:0042446 hormone biosynthetic process IMP
 biological_processGO:0048260 positive regulation of receptor-mediated endocytosis ISO
 biological_processGO:0055072 iron ion homeostasis ISO
 biological_processGO:0060586 multicellular organismal iron ion homeostasis IMP
 biological_processGO:0071281 cellular response to iron ion ISO
 biological_processGO:0090277 positive regulation of peptide hormone secretion ISO
 biological_processGO:0098711 iron ion import across plasma membrane ISO
 biological_processGO:1900121 negative regulation of receptor binding ISO
 biological_processGO:1900122 positive regulation of receptor binding ISO
 biological_processGO:1900390 regulation of iron ion import ISO
 biological_processGO:1904283 negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I ISO
 biological_processGO:1904434 positive regulation of ferrous iron binding ISO
 biological_processGO:1904437 positive regulation of transferrin receptor binding ISO
 biological_processGO:2000008 regulation of protein localization to cell surface ISO
 biological_processGO:2000059 negative regulation of ubiquitin-dependent protein catabolic process ISO
 biological_processGO:2000272 negative regulation of signaling receptor activity ISO
 biological_processGO:2000273 positive regulation of signaling receptor activity ISO
 biological_processGO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 cellular_componentGO:0045177 apical part of cell ISO
 cellular_componentGO:0045178 basal part of cell ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0055037 recycling endosome ISO
 cellular_componentGO:1990357 terminal web ISO
 cellular_componentGO:1990712 HFE-transferrin receptor complex ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0030881 beta-2-microglobulin binding ISO
 molecular_functionGO:0039706 co-receptor binding ISO
 molecular_functionGO:0046703 natural killer cell lectin-like receptor binding IBA
 molecular_functionGO:1990459 transferrin receptor binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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