15251


Mus musculus (NCBI)

Features
Gene ID: 15251
  
Biological name :
  
Synonyms : AA959795|HIF-1-alpha|HIF1-alpha|HIF1alpha|MOP1|bHLHe78 / Hif1a / hypoxia inducible factor 1, alpha subunit
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1416035_at (Mouse Genome 430 2.0 Array)   1427418_a_at (Mouse Genome 430 2.0 Array)   1431981_at (Mouse Genome 430 2.0 Array)   1448183_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1039739780
RefSeq - 226061948
RefSeq - 568978823
RefSeq - 927028881
RefSeq - 927028883
RefSeq - NC_000078.6
RefSeq - NP_001300848.1
RefSeq - NP_001300849.1
RefSeq - NP_034561.2
RefSeq - XP_006515541.1
RefSeq - XP_017170450.1
RefSeq - NM_001313919.1
RefSeq - NM_001313920.1
RefSeq - NM_010431.2
RefSeq - XM_017314961.1
RefSeq - XM_006515478.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000021109 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0001837 epithelial to mesenchymal transition IMP
 biological_processGO:0001892 embryonic placenta development IMP
 biological_processGO:0001922 B-1 B cell homeostasis IMP
 biological_processGO:0001944 vasculature development IGI
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0002052 positive regulation of neuroblast proliferation IGI
 biological_processGO:0002248 connective tissue replacement involved in inflammatory response wound healing IMP
 biological_processGO:0003151 outflow tract morphogenesis IMP
 biological_processGO:0003208 cardiac ventricle morphogenesis IMP
 biological_processGO:0006089 lactate metabolic process IMP
 biological_processGO:0006110 regulation of glycolytic process IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II ISO
 biological_processGO:0006879 cellular iron ion homeostasis IMP
 biological_processGO:0007165 signal transduction ISO
 biological_processGO:0007595 lactation IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008542 visual learning IMP
 biological_processGO:0010468 regulation of gene expression ISO
 biological_processGO:0010508 positive regulation of autophagy IMP
 biological_processGO:0010573 vascular endothelial growth factor production ISO
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0010634 positive regulation of epithelial cell migration IMP
 biological_processGO:0010870 positive regulation of receptor biosynthetic process ISO
 biological_processGO:0014850 response to muscle activity IMP
 biological_processGO:0016239 positive regulation of macroautophagy IMP
 biological_processGO:0019896 axonal transport of mitochondrion ISO
 biological_processGO:0021502 neural fold elevation formation IMP
 biological_processGO:0021987 cerebral cortex development IMP
 biological_processGO:0030154 cell differentiation IMP
 biological_processGO:0030279 negative regulation of ossification IMP
 biological_processGO:0030502 negative regulation of bone mineralization IMP
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway IMP
 biological_processGO:0032007 negative regulation of TOR signaling IMP
 biological_processGO:0032364 oxygen homeostasis ISO
 biological_processGO:0032909 regulation of transforming growth factor beta2 production ISO
 biological_processGO:0032963 collagen metabolic process IMP
 biological_processGO:0035162 embryonic hemopoiesis IMP
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0042541 hemoglobin biosynthetic process IMP
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress ISO
 biological_processGO:0045648 positive regulation of erythrocyte differentiation IMP
 biological_processGO:0045722 positive regulation of gluconeogenesis ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045906 negative regulation of vasoconstriction ISO
 biological_processGO:0045926 negative regulation of growth IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046716 muscle cell cellular homeostasis IMP
 biological_processGO:0046886 positive regulation of hormone biosynthetic process ISO
 biological_processGO:0048514 blood vessel morphogenesis IMP
 biological_processGO:0048546 digestive tract morphogenesis IMP
 biological_processGO:0048593 camera-type eye morphogenesis IGI
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050790 regulation of catalytic activity IMP
 biological_processGO:0051216 cartilage development IMP
 biological_processGO:0051541 elastin metabolic process IMP
 biological_processGO:0060574 intestinal epithelial cell maturation IMP
 biological_processGO:0060992 response to fungicide ISO
 biological_processGO:0061030 epithelial cell differentiation involved in mammary gland alveolus development IMP
 biological_processGO:0061072 iris morphogenesis IGI
 biological_processGO:0061298 retina vasculature development in camera-type eye IMP
 biological_processGO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia ISO
 biological_processGO:0070243 regulation of thymocyte apoptotic process IGI
 biological_processGO:0070244 negative regulation of thymocyte apoptotic process IMP
 biological_processGO:0071456 cellular response to hypoxia ISO
 biological_processGO:0071542 dopaminergic neuron differentiation IMP
 biological_processGO:0097411 hypoxia-inducible factor-1alpha signaling pathway IDA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II ISO
 biological_processGO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway ISO
 biological_processGO:1903599 positive regulation of autophagy of mitochondrion IMP
 biological_processGO:1903715 regulation of aerobic respiration IMP
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process IMP
 biological_processGO:2001054 negative regulation of mesenchymal cell apoptotic process IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005667 transcription factor complex ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016604 nuclear body ISO
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0031514 motile cilium IDA
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex ISO
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISO
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0002039 p53 binding ISO
 molecular_functionGO:0003677 DNA binding IGI
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0035035 histone acetyltransferase binding ISO
 molecular_functionGO:0035257 nuclear hormone receptor binding ISO
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0051879 Hsp90 protein binding ISO
 molecular_functionGO:0070888 E-box binding IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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