16000


Mus musculus (NCBI)

Features
Gene ID: 16000
  
Biological name :
  
Synonyms : C730016P09Rik|Igf-1|Igf-I / Igf1 / insulin-like growth factor 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1419519_at (Mouse Genome 430 2.0 Array)   1434413_at (Mouse Genome 430 2.0 Array)   1437401_at (Mouse Genome 430 2.0 Array)   1452014_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 568966757
RefSeq - 1039732194
RefSeq - 1039732196
RefSeq - 163659889
RefSeq - 163659892
RefSeq - 163659894
RefSeq - 163659896
RefSeq - 568966745
RefSeq - 568966749
RefSeq - 568966751
RefSeq - 1039732190
RefSeq - 568966759
RefSeq - 568966763
RefSeq - 930155590
RefSeq - NC_000076.6
RefSeq - NP_001104744.1
RefSeq - NP_001104745.1
RefSeq - NP_001104746.1
RefSeq - NP_001300939.1
RefSeq - NP_034642.2
RefSeq - XP_006513318.1
RefSeq - XP_006513320.1
RefSeq - XP_006513321.1
RefSeq - XP_006513324.1
RefSeq - XP_006513325.1
RefSeq - XP_006513327.1
RefSeq - XP_017169299.1
RefSeq - XP_017169300.1
RefSeq - XP_017169301.1
RefSeq - XM_006513261.2
RefSeq - NM_001111274.1
RefSeq - NM_001111275.2
RefSeq - NM_001111276.1
RefSeq - NM_001314010.1
RefSeq - NM_010512.5
RefSeq - NM_184052.3
RefSeq - XM_006513262.2
RefSeq - XM_006513264.3
RefSeq - XM_017313810.1
RefSeq - XM_017313811.1
RefSeq - XM_017313812.1
RefSeq - XM_006513255.2
RefSeq - XM_006513257.1
RefSeq - XM_006513258.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000020053 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity ISO
 biological_processGO:0001649 osteoblast differentiation IEP
 biological_processGO:0001775 cell activation ISO
 biological_processGO:0001932 regulation of protein phosphorylation IDA
 biological_processGO:0001974 blood vessel remodeling IMP
 biological_processGO:0002683 negative regulation of immune system process ISO
 biological_processGO:0006417 regulation of translation ISO
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0007608 sensory perception of smell TAS
 biological_processGO:0007613 memory ISO
 biological_processGO:0007623 circadian rhythm IEP
 biological_processGO:0008283 cell proliferation ISO
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0009408 response to heat ISO
 biological_processGO:0010001 glial cell differentiation IMP
 biological_processGO:0010468 regulation of gene expression ISO
 biological_processGO:0010560 positive regulation of glycoprotein biosynthetic process ISO
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0010656 negative regulation of muscle cell apoptotic process ISO
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration ISO
 biological_processGO:0014896 muscle hypertrophy ISO
 biological_processGO:0014904 myotube cell development ISO
 biological_processGO:0014911 positive regulation of smooth muscle cell migration ISO
 biological_processGO:0021940 positive regulation of cerebellar granule cell precursor proliferation IDA
 biological_processGO:0030104 water homeostasis IGI
 biological_processGO:0030166 proteoglycan biosynthetic process ISO
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0030324 lung development IGI
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030879 mammary gland development IMP
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0032148 activation of protein kinase B activity ISO
 biological_processGO:0032878 regulation of establishment or maintenance of cell polarity IDA
 biological_processGO:0033143 regulation of intracellular steroid hormone receptor signaling pathway ISO
 biological_processGO:0033160 positive regulation of protein import into nucleus, translocation ISO
 biological_processGO:0034392 negative regulation of smooth muscle cell apoptotic process ISO
 biological_processGO:0035264 multicellular organism growth IDA
 biological_processGO:0035630 bone mineralization involved in bone maturation ISO
 biological_processGO:0042104 positive regulation of activated T cell proliferation ISO
 biological_processGO:0042127 regulation of cell proliferation ISO
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0043388 positive regulation of DNA binding ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0043491 protein kinase B signaling ISO
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway ISO
 biological_processGO:0045428 regulation of nitric oxide biosynthetic process IMP
 biological_processGO:0045445 myoblast differentiation ISO
 biological_processGO:0045471 response to ethanol ISO
 biological_processGO:0045600 positive regulation of fat cell differentiation ISO
 biological_processGO:0045669 positive regulation of osteoblast differentiation ISO
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process ISO
 biological_processGO:0045821 positive regulation of glycolytic process ISO
 biological_processGO:0045840 positive regulation of mitotic nuclear division ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046326 positive regulation of glucose import ISO
 biological_processGO:0046579 positive regulation of Ras protein signal transduction ISO
 biological_processGO:0048009 insulin-like growth factor receptor signaling pathway ISO
 biological_processGO:0048015 phosphatidylinositol-mediated signaling ISO
 biological_processGO:0048146 positive regulation of fibroblast proliferation ISO
 biological_processGO:0048286 lung alveolus development IMP
 biological_processGO:0048468 cell development IMP
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IMP
 biological_processGO:0048839 inner ear development IDA
 biological_processGO:0050650 chondroitin sulfate proteoglycan biosynthetic process IDA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation ISO
 biological_processGO:0050714 positive regulation of protein secretion ISO
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0050732 negative regulation of peptidyl-tyrosine phosphorylation IMP
 biological_processGO:0050821 protein stabilization ISO
 biological_processGO:0050974 detection of mechanical stimulus involved in sensory perception ISO
 biological_processGO:0051246 regulation of protein metabolic process IGI
 biological_processGO:0051450 myoblast proliferation ISO
 biological_processGO:0051897 positive regulation of protein kinase B signaling IDA
 biological_processGO:0051924 regulation of calcium ion transport ISO
 biological_processGO:0060252 positive regulation of glial cell proliferation ISO
 biological_processGO:0060283 negative regulation of oocyte development ISO
 biological_processGO:0060426 lung vasculature development IMP
 biological_processGO:0060463 lung lobe morphogenesis IMP
 biological_processGO:0060509 type I pneumocyte differentiation IMP
 biological_processGO:0060510 type II pneumocyte differentiation IMP
 biological_processGO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis IMP
 biological_processGO:0060736 prostate gland growth IMP
 biological_processGO:0060740 prostate gland epithelium morphogenesis IMP
 biological_processGO:0060741 prostate gland stromal morphogenesis IMP
 biological_processGO:0060766 negative regulation of androgen receptor signaling pathway IMP
 biological_processGO:0061051 positive regulation of cell growth involved in cardiac muscle cell development ISO
 biological_processGO:0070371 ERK1 and ERK2 cascade ISO
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IGI
 biological_processGO:0070886 positive regulation of calcineurin-NFAT signaling cascade ISO
 biological_processGO:0071333 cellular response to glucose stimulus IDA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity ISO
 biological_processGO:0090031 positive regulation of steroid hormone biosynthetic process ISO
 biological_processGO:0090201 negative regulation of release of cytochrome c from mitochondria IDA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IDA
 biological_processGO:1900142 negative regulation of oligodendrocyte apoptotic process ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:1904075 positive regulation of trophectodermal cell proliferation ISO
 biological_processGO:1904193 negative regulation of cholangiocyte apoptotic process ISO
 biological_processGO:1904646 cellular response to amyloid-beta ISO
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation ISO
 biological_processGO:1905460 negative regulation of vascular associated smooth muscle cell apoptotic process ISO
 biological_processGO:1905564 positive regulation of vascular endothelial cell proliferation ISO
 biological_processGO:1990314 cellular response to insulin-like growth factor stimulus IMP
 biological_processGO:2000288 positive regulation of myoblast proliferation IMP
 biological_processGO:2000679 positive regulation of transcription regulatory region DNA binding ISO
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005614 interstitial matrix ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0031091 platelet alpha granule ISO
 cellular_componentGO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex ISO
 cellular_componentGO:0042567 insulin-like growth factor ternary complex TAS
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0070382 exocytic vesicle IDA
 molecular_functionGO:0005158 insulin receptor binding ISO
 molecular_functionGO:0005159 insulin-like growth factor receptor binding ISO
 molecular_functionGO:0005178 integrin binding ISO
 molecular_functionGO:0005179 hormone activity ISO
 molecular_functionGO:0005496 steroid binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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