16001


Mus musculus (NCBI)

Features
Gene ID: 16001
  
Biological name :
  
Synonyms : A330103N21Rik|CD221|D930020L01|IGF-1R|hyft / Igf1r / insulin-like growth factor I receptor
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1426565_at (Mouse Genome 430 2.0 Array)   1428967_at (Mouse Genome 430 2.0 Array)   1446303_at (Mouse Genome 430 2.0 Array)   1452108_at (Mouse Genome 430 2.0 Array)   1452982_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1039777320
RefSeq - 112983656
RefSeq - 568947359
RefSeq - 568947361
RefSeq - 568947363
RefSeq - 568947365
RefSeq - 568947367
RefSeq - NC_000073.6
RefSeq - NP_034643.2
RefSeq - XP_006540704.1
RefSeq - XP_006540705.1
RefSeq - XP_006540706.1
RefSeq - XP_006540707.1
RefSeq - XP_006540708.1
RefSeq - XP_017177475.1
RefSeq - NM_010513.2
RefSeq - XM_017321986.1
RefSeq - XM_006540641.3
RefSeq - XM_006540642.3
RefSeq - XM_006540643.3
RefSeq - XM_006540644.3
RefSeq - XM_006540645.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000005533 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IBA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006955 immune response ISO
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007409 axonogenesis ISO
 biological_processGO:0007420 brain development IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008286 insulin receptor signaling pathway ISO
 biological_processGO:0008544 epidermis development IMP
 biological_processGO:0009887 animal organ morphogenesis IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010656 negative regulation of muscle cell apoptotic process ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0021549 cerebellum development ISO
 biological_processGO:0030010 establishment of cell polarity ISO
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030238 male sex determination IMP
 biological_processGO:0030325 adrenal gland development IGI
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030879 mammary gland development IMP
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0031175 neuron projection development ISO
 biological_processGO:0032467 positive regulation of cytokinesis ISO
 biological_processGO:0032869 cellular response to insulin stimulus IMP
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0033690 positive regulation of osteoblast proliferation ISO
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation ISO
 biological_processGO:0042593 glucose homeostasis IBA
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043243 positive regulation of protein complex disassembly ISO
 biological_processGO:0043409 negative regulation of MAPK cascade IMP
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0044849 estrous cycle ISO
 biological_processGO:0045471 response to ethanol ISO
 biological_processGO:0045840 positive regulation of mitotic nuclear division IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IGI
 biological_processGO:0046328 regulation of JNK cascade ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048009 insulin-like growth factor receptor signaling pathway ISO
 biological_processGO:0048015 phosphatidylinositol-mediated signaling ISO
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0048680 positive regulation of axon regeneration ISO
 biological_processGO:0051054 positive regulation of DNA metabolic process ISO
 biological_processGO:0051262 protein tetramerization ISO
 biological_processGO:0051291 protein heterooligomerization ISO
 biological_processGO:0051389 inactivation of MAPKK activity ISO
 biological_processGO:0051446 positive regulation of meiotic cell cycle IGI
 biological_processGO:0051897 positive regulation of protein kinase B signaling IMP
 biological_processGO:0051898 negative regulation of protein kinase B signaling IMP
 biological_processGO:0060740 prostate gland epithelium morphogenesis IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071333 cellular response to glucose stimulus IMP
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus ISO
 biological_processGO:0090031 positive regulation of steroid hormone biosynthetic process ISO
 biological_processGO:0097062 dendritic spine maintenance ISO
 biological_processGO:0097242 amyloid-beta clearance ISO
 biological_processGO:1902065 response to L-glutamate ISO
 biological_processGO:1903944 negative regulation of hepatocyte apoptotic process ISO
 biological_processGO:1904193 negative regulation of cholangiocyte apoptotic process ISO
 biological_processGO:1904385 cellular response to angiotensin ISO
 biological_processGO:1904646 cellular response to amyloid-beta ISO
 biological_processGO:1990314 cellular response to insulin-like growth factor stimulus ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005899 insulin receptor complex IBA
 cellular_componentGO:0005901 caveola ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0030315 T-tubule ISO
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex ISO
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0043235 receptor complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001965 G-protein alpha-subunit binding ISO
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005009 insulin-activated receptor activity IBA
 molecular_functionGO:0005010 insulin-like growth factor-activated receptor activity ISO
 molecular_functionGO:0005158 insulin receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005520 insulin-like growth factor binding ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0031994 insulin-like growth factor I binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding ISO
 molecular_functionGO:0043559 insulin binding ISO
 molecular_functionGO:0043560 insulin receptor substrate binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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