16149


Mus musculus (NCBI)

Features
Gene ID: 16149
  
Biological name :
  
Synonyms : Cd74 / CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) / CLIP|DHLAG|HLADG|Ia-GAMMA|Ii
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1425519_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_001036070.1
RefSeq - NP_034675.1
RefSeq - NC_000084.6
RefSeq - 110624770
RefSeq - 29789020
RefSeq - NM_001042605.1
RefSeq - NM_010545.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000024610 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity ISO
 biological_processGO:0001516 prostaglandin biosynthetic process ISO
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0001961 positive regulation of cytokine-mediated signaling pathway ISO
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002606 positive regulation of dendritic cell antigen processing and presentation IDA
 biological_processGO:0002792 negative regulation of peptide secretion ISO
 biological_processGO:0002821 positive regulation of adaptive immune response NAS
 biological_processGO:0002830 positive regulation of type 2 immune response IMP
 biological_processGO:0002906 negative regulation of mature B cell apoptotic process IMP
 biological_processGO:0006886 intracellular protein transport IMP
 biological_processGO:0006952 defense response IMP
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction ISO
 biological_processGO:0008283 cell proliferation ISO
 biological_processGO:0016064 immunoglobulin mediated immune response IMP
 biological_processGO:0019882 antigen processing and presentation IMP
 biological_processGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II IMP
 biological_processGO:0030890 positive regulation of B cell proliferation ISO
 biological_processGO:0033674 positive regulation of kinase activity ISO
 biological_processGO:0035691 macrophage migration inhibitory factor signaling pathway IDA
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator ISO
 biological_processGO:0045059 positive thymic T cell selection IMP
 biological_processGO:0045060 negative thymic T cell selection IMP
 biological_processGO:0045089 positive regulation of innate immune response IC
 biological_processGO:0045581 negative regulation of T cell differentiation IMP
 biological_processGO:0045582 positive regulation of T cell differentiation IMP
 biological_processGO:0045657 positive regulation of monocyte differentiation ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0046598 positive regulation of viral entry into host cell ISO
 biological_processGO:0048146 positive regulation of fibroblast proliferation ISO
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0051085 chaperone cofactor-dependent protein refolding IMP
 biological_processGO:0051290 protein heterotetramerization ISO
 biological_processGO:0060907 positive regulation of macrophage cytokine production IDA
 biological_processGO:0065003 protein-containing complex assembly IDA
 biological_processGO:0070206 protein trimerization IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis IDA
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISO
 biological_processGO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production IDA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005771 multivesicular body IDA
 cellular_componentGO:0005773 vacuole ISO
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane IMP
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0035692 macrophage migration inhibitory factor receptor complex ISO
 cellular_componentGO:0035693 NOS2-CD74 complex IDA
 cellular_componentGO:0042613 MHC class II protein complex IDA
 molecular_functionGO:0001540 amyloid-beta binding ISO
 molecular_functionGO:0004896 cytokine receptor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019955 cytokine binding ISO
 molecular_functionGO:0023026 MHC class II protein complex binding ISO
 molecular_functionGO:0035718 macrophage migration inhibitory factor binding ISO
 molecular_functionGO:0042289 MHC class II protein binding IPI
 molecular_functionGO:0042609 CD4 receptor binding ISO
 molecular_functionGO:0042658 MHC class II protein binding, via antigen binding groove ISO
 molecular_functionGO:0044183 protein binding involved in protein folding ISO
 molecular_functionGO:0050998 nitric-oxide synthase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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