16160


Mus musculus (NCBI)

Features
Gene ID: 16160
  
Biological name :
  
Synonyms : Il12b / Il-12b|Il-12p40|Il12p40|p40 / interleukin 12b
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1419530_at (Mouse Genome 430 2.0 Array)   1449497_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 735997434
RefSeq - NC_000077.6
RefSeq - NP_001290173.1
RefSeq - NM_001303244.1
RefSeq - NM_008352.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000004296 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001916 positive regulation of T cell mediated cytotoxicity IDA
 biological_processGO:0002230 positive regulation of defense response to virus by host ISO
 biological_processGO:0002323 natural killer cell activation involved in immune response ISO
 biological_processGO:0002827 positive regulation of T-helper 1 type immune response ISO
 biological_processGO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target ISO
 biological_processGO:0002862 negative regulation of inflammatory response to antigenic stimulus IMP
 biological_processGO:0007050 cell cycle arrest ISO
 biological_processGO:0007166 cell surface receptor signaling pathway IDA
 biological_processGO:0008283 cell proliferation IGI
 biological_processGO:0010033 response to organic substance IDA
 biological_processGO:0010224 response to UV-B ISO
 biological_processGO:0010536 positive regulation of activation of Janus kinase activity ISO
 biological_processGO:0016477 cell migration ISO
 biological_processGO:0019233 sensory perception of pain ISO
 biological_processGO:0030101 natural killer cell activation ISO
 biological_processGO:0032609 interferon-gamma production IGI
 biological_processGO:0032693 negative regulation of interleukin-10 production ISO
 biological_processGO:0032700 negative regulation of interleukin-17 production ISO
 biological_processGO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production ISO
 biological_processGO:0032729 positive regulation of interferon-gamma production ISO
 biological_processGO:0032733 positive regulation of interleukin-10 production ISO
 biological_processGO:0032735 positive regulation of interleukin-12 production ISO
 biological_processGO:0032740 positive regulation of interleukin-17 production ISO
 biological_processGO:0032760 positive regulation of tumor necrosis factor production ISO
 biological_processGO:0032816 positive regulation of natural killer cell activation ISO
 biological_processGO:0032819 positive regulation of natural killer cell proliferation ISO
 biological_processGO:0032946 positive regulation of mononuclear cell proliferation ISO
 biological_processGO:0034393 positive regulation of smooth muscle cell apoptotic process ISO
 biological_processGO:0035744 T-helper 1 cell cytokine production IGI
 biological_processGO:0042093 T-helper cell differentiation ISO
 biological_processGO:0042102 positive regulation of T cell proliferation ISO
 biological_processGO:0042104 positive regulation of activated T cell proliferation ISO
 biological_processGO:0042509 regulation of tyrosine phosphorylation of STAT protein ISO
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISO
 biological_processGO:0042832 defense response to protozoan IMP
 biological_processGO:0044130 negative regulation of growth of symbiont in host IMP
 biological_processGO:0045672 positive regulation of osteoclast differentiation ISO
 biological_processGO:0045785 positive regulation of cell adhesion ISO
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050671 positive regulation of lymphocyte proliferation ISO
 biological_processGO:0050829 defense response to Gram-negative bacterium ISO
 biological_processGO:0051135 positive regulation of NK T cell activation ISO
 biological_processGO:0051142 positive regulation of NK T cell proliferation ISO
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0071222 cellular response to lipopolysaccharide IDA
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043514 interleukin-12 complex ISO
 cellular_componentGO:0070743 interleukin-23 complex ISO
 molecular_functionGO:0004896 cytokine receptor activity IEA
 molecular_functionGO:0005125 cytokine activity ISO
 molecular_functionGO:0005126 cytokine receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity ISO
 molecular_functionGO:0042164 interleukin-12 alpha subunit binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0045519 interleukin-23 receptor binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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