16176


Mus musculus (NCBI)

Features
Gene ID: 16176
  
Biological name :
  
Synonyms : Il1b / IL-1beta|Il-1b / interleukin 1 beta
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1449399_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6680415
RefSeq - XP_006498858.1
RefSeq - NC_000068.7
RefSeq - 568915531
RefSeq - NP_032387.1
RefSeq - NM_008361.4
RefSeq - XM_006498795.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000027398 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0000165 MAPK cascade ISO
 biological_processGO:0000187 activation of MAPK activity ISO
 biological_processGO:0001660 fever generation IEA
 biological_processGO:0001666 response to hypoxia IBA
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0002437 inflammatory response to antigenic stimulus IBA
 biological_processGO:0002439 chronic inflammatory response to antigenic stimulus IBA
 biological_processGO:0006954 inflammatory response ISO
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration ISO
 biological_processGO:0007613 memory ISO
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0009408 response to heat IBA
 biological_processGO:0009743 response to carbohydrate IDA
 biological_processGO:0010193 response to ozone IBA
 biological_processGO:0010332 response to gamma radiation IBA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition ISO
 biological_processGO:0010829 negative regulation of glucose transmembrane transport IDA
 biological_processGO:0010942 positive regulation of cell death ISO
 biological_processGO:0014050 negative regulation of glutamate secretion ISO
 biological_processGO:0014070 response to organic cyclic compound IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway ISO
 biological_processGO:0030213 hyaluronan biosynthetic process ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030593 neutrophil chemotaxis IDA
 biological_processGO:0030728 ovulation IBA
 biological_processGO:0030730 sequestering of triglyceride ISO
 biological_processGO:0031622 positive regulation of fever generation IDA
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway ISO
 biological_processGO:0032308 positive regulation of prostaglandin secretion IDA
 biological_processGO:0032355 response to estradiol IBA
 biological_processGO:0032496 response to lipopolysaccharide IMP
 biological_processGO:0032611 interleukin-1 beta production IGI
 biological_processGO:0032635 interleukin-6 production IDA
 biological_processGO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production ISO
 biological_processGO:0032729 positive regulation of interferon-gamma production ISO
 biological_processGO:0032755 positive regulation of interleukin-6 production ISO
 biological_processGO:0032757 positive regulation of interleukin-8 production ISO
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade ISO
 biological_processGO:0033092 positive regulation of immature T cell proliferation in thymus ISO
 biological_processGO:0033198 response to ATP IMP
 biological_processGO:0033280 response to vitamin D IBA
 biological_processGO:0033591 response to L-ascorbic acid IBA
 biological_processGO:0034116 positive regulation of heterotypic cell-cell adhesion ISO
 biological_processGO:0035176 social behavior ISO
 biological_processGO:0035234 ectopic germ cell programmed cell death IGI
 biological_processGO:0035505 positive regulation of myosin light chain kinase activity ISO
 biological_processGO:0035634 response to stilbenoid IBA
 biological_processGO:0035690 cellular response to drug ISO
 biological_processGO:0035902 response to immobilization stress IBA
 biological_processGO:0042060 wound healing IBA
 biological_processGO:0042102 positive regulation of T cell proliferation ISO
 biological_processGO:0042493 response to drug IBA
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0043278 response to morphine IBA
 biological_processGO:0043407 negative regulation of MAP kinase activity IDA
 biological_processGO:0043434 response to peptide hormone IBA
 biological_processGO:0043491 protein kinase B signaling ISO
 biological_processGO:0043507 positive regulation of JUN kinase activity ISO
 biological_processGO:0043525 positive regulation of neuron apoptotic process ISO
 biological_processGO:0045080 positive regulation of chemokine biosynthetic process IDA
 biological_processGO:0045086 positive regulation of interleukin-2 biosynthetic process ISO
 biological_processGO:0045410 positive regulation of interleukin-6 biosynthetic process IDA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process ISO
 biological_processGO:0045471 response to ethanol IBA
 biological_processGO:0045665 negative regulation of neuron differentiation ISO
 biological_processGO:0045687 positive regulation of glial cell differentiation ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0045833 negative regulation of lipid metabolic process IDA
 biological_processGO:0045840 positive regulation of mitotic nuclear division ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046330 positive regulation of JNK cascade ISO
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IDA
 biological_processGO:0048711 positive regulation of astrocyte differentiation ISO
 biological_processGO:0050691 regulation of defense response to virus by host IDA
 biological_processGO:0050766 positive regulation of phagocytosis ISO
 biological_processGO:0050768 negative regulation of neurogenesis ISO
 biological_processGO:0050796 regulation of insulin secretion ISO
 biological_processGO:0050805 negative regulation of synaptic transmission IMP
 biological_processGO:0050900 leukocyte migration IDA
 biological_processGO:0050995 negative regulation of lipid catabolic process ISO
 biological_processGO:0050996 positive regulation of lipid catabolic process IDA
 biological_processGO:0050999 regulation of nitric-oxide synthase activity ISO
 biological_processGO:0051044 positive regulation of membrane protein ectodomain proteolysis ISO
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0051384 response to glucocorticoid IBA
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0060559 positive regulation of calcidiol 1-monooxygenase activity ISO
 biological_processGO:0070164 negative regulation of adiponectin secretion IDA
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070487 monocyte aggregation ISO
 biological_processGO:0071222 cellular response to lipopolysaccharide IBA
 biological_processGO:0071236 cellular response to antibiotic IBA
 biological_processGO:0071260 cellular response to mechanical stimulus IBA
 biological_processGO:0071310 cellular response to organic substance ISO
 biological_processGO:0071333 cellular response to glucose stimulus IBA
 biological_processGO:0071398 cellular response to fatty acid IBA
 biological_processGO:0071407 cellular response to organic cyclic compound ISO
 biological_processGO:0071548 response to dexamethasone IBA
 biological_processGO:0071639 positive regulation of monocyte chemotactic protein-1 production ISO
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis ISO
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IMP
 biological_processGO:1900745 positive regulation of p38MAPK cascade IGI
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling ISO
 biological_processGO:1903140 regulation of establishment of endothelial barrier ISO
 biological_processGO:2000173 negative regulation of branching morphogenesis of a nerve ISO
 biological_processGO:2000178 negative regulation of neural precursor cell proliferation ISO
 biological_processGO:2000556 positive regulation of T-helper 1 cell cytokine production ISO
 biological_processGO:2000778 positive regulation of interleukin-6 secretion IDA
 biological_processGO:2000866 positive regulation of estradiol secretion IBA
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0030141 secretory granule IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031982 vesicle IDA
 molecular_functionGO:0005125 cytokine activity ISO
 molecular_functionGO:0005149 interleukin-1 receptor binding IBA
 molecular_functionGO:0005178 integrin binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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