ENSMUSG00000027398


Mus musculus

Features
Gene ID: ENSMUSG00000027398
  
Biological name :Il1b
  
Synonyms : Il1b / Interleukin-1 beta / P10749
  
Possible biological names infered from orthology : P01584
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: F1
Gene start: 129364570
Gene end: 129371139
  
Corresponding Affymetrix probe sets: 10487597 (MoGene1.0st)   1449399_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028881
NCBI entrez gene - 16176     See in Manteia.
MGI - MGI:96543
RefSeq - NM_008361
RefSeq - XM_006498795
RefSeq Peptide - NP_032387
swissprot - P10749
Ensembl - ENSMUSG00000027398
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il1bENSDARG00000098700Danio rerio
 IL1BENSGALG00000029940Gallus gallus
 IL1BENSG00000125538Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000975  Interleukin-1 family
 IPR003296  Interleukin-1 beta
 IPR003502  Interleukin-1 propeptide
 IPR008996  Cytokine IL1/FGF
 IPR020877  Interleukin-1 conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0001660 fever generation IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006954 inflammatory response ISO
 biological_processGO:0006955 immune response IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009743 response to carbohydrate IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0010829 negative regulation of glucose transmembrane transport IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0030213 hyaluronan biosynthetic process IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030593 neutrophil chemotaxis IDA
 biological_processGO:0030730 sequestering of triglyceride IEA
 biological_processGO:0031622 positive regulation of fever generation IDA
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032308 positive regulation of prostaglandin secretion IDA
 biological_processGO:0032496 response to lipopolysaccharide IMP
 biological_processGO:0032611 interleukin-1 beta production IGI
 biological_processGO:0032635 interleukin-6 production IDA
 biological_processGO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production ISO
 biological_processGO:0032757 positive regulation of interleukin-8 production IEA
 biological_processGO:0033198 response to ATP IMP
 biological_processGO:0034116 positive regulation of heterotypic cell-cell adhesion IEA
 biological_processGO:0035234 ectopic germ cell programmed cell death IGI
 biological_processGO:0035505 positive regulation of myosin light chain kinase activity IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IGI
 biological_processGO:0043407 negative regulation of MAP kinase activity IDA
 biological_processGO:0043491 protein kinase B signaling IEA
 biological_processGO:0045080 positive regulation of chemokine biosynthetic process IDA
 biological_processGO:0045086 positive regulation of interleukin-2 biosynthetic process IEA
 biological_processGO:0045410 positive regulation of interleukin-6 biosynthetic process IDA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045833 negative regulation of lipid metabolic process IDA
 biological_processGO:0045840 positive regulation of mitotic nuclear division IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 biological_processGO:0046330 positive regulation of JNK cascade IGI
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IDA
 biological_processGO:0050691 regulation of defense response to virus by host IDA
 biological_processGO:0050766 positive regulation of phagocytosis IEA
 biological_processGO:0050796 regulation of insulin secretion IEA
 biological_processGO:0050805 negative regulation of synaptic transmission IMP
 biological_processGO:0050900 leukocyte migration IDA
 biological_processGO:0050995 negative regulation of lipid catabolic process IEA
 biological_processGO:0050996 positive regulation of lipid catabolic process IDA
 biological_processGO:0050999 regulation of nitric-oxide synthase activity IDA
 biological_processGO:0051044 positive regulation of membrane protein ectodomain proteolysis IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0060559 positive regulation of calcidiol 1-monooxygenase activity IEA
 biological_processGO:0070164 negative regulation of adiponectin secretion IDA
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0070487 monocyte aggregation IEA
 biological_processGO:0071260 cellular response to mechanical stimulus IEA
 biological_processGO:0071310 cellular response to organic substance IEA
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:0071639 positive regulation of monocyte chemotactic protein-1 production IEA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IMP
 biological_processGO:1900745 positive regulation of p38MAPK cascade IGI
 biological_processGO:1903140 regulation of establishment of endothelial barrier IEA
 biological_processGO:2000778 positive regulation of interleukin-6 secretion IDA
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030141 secretory granule IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0070062 extracellular exosome IEA
 molecular_functionGO:0005125 cytokine activity ISO
 molecular_functionGO:0005149 interleukin-1 receptor binding IBA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-1 processing
CLEC7A/inflammasome pathway
Interleukin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000920 abnormal myelination "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Muc2M1Btlr/Muc2+
Genetic Background: C57BL/6J-Muc2M1Btlr

 MP:0000953 abnormal oligodendrocyte morphology "anomalous structure, number or composition of the neuroglia of the central nervous system that form the insulating myelin sheath of axons in the CNS" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Muc2M1Btlr/Muc2+
Genetic Background: C57BL/6J-Muc2M1Btlr

 MP:0001194 dermatitis "inflammation of the skin" [J:65146]
Show

Allelic Composition: Mylktm1.1Bph/Mylktm1.2Bph,Tg(Myh11-cre,-EGFP)2Mik/0
Genetic Background: involves: C57BL/6 * C57BL/6N * DBA/2

 MP:0001273 decreased metastatic potential 
Show

Allelic Composition: Ifngr1tm1Agt/Ifngr1tm1Agt,Tg(GZMB-Tax)#Lera/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001876 decreased inflammatory response "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

 MP:0002410 decreased susceptibility to viral infection "reduced likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ifngr1tm1Agt/Ifngr1tm1Agt,Tg(GZMB-Tax)#Lera/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Muc2M1Btlr/Muc2+
Genetic Background: C57BL/6J-Muc2M1Btlr

Allelic Composition: Il18tm1Aki/Il18tm1Aki,Il1btm1Dch/Il1btm1Dch
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002451 abnormal macrophage physiology "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ifngr1tm1Agt/Ifngr1tm1Agt,Tg(GZMB-Tax)#Lera/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002665 decreased circulating corticosterone level "less than the normal blood concentration of this adrenocortical steroid; induces glycogen deposition and regulates sodium conservation and potassium secretion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Plp1jp-4J/Y
Genetic Background: involves: C3H/HeJ * C57BL/6J

Allelic Composition: Il1atm1Yiw/Il1atm1Yiw,Il1btm1Yiw/Il1btm1Yiw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003447 reduced tumor growth/size "less than expected development of tumorous growth when compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65383]
Show

Allelic Composition: Ifngr1tm1Agt/Ifngr1tm1Agt,Tg(GZMB-Tax)#Lera/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003829 impaired febrile response "reduced or absent febrile response to exogenous or endogenous pyrogens" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:70534]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

Allelic Composition: Il1btm1Yiw/Il1btm1Yiw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Il1atm1Yiw/Il1atm1Yiw,Il1btm1Yiw/Il1btm1Yiw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003945 abnormal lymphocyte physiology "abnormal function of any of the white blood cells that includes B cells, T cells, and NK cells " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

 MP:0004800 decreased susceptibility to experimental autoimmune encephalomyelitis "reduced likelihood that an organism will develop disease symptoms similar to human multiple sclerosis upon induction with antigens to Myelin Basic Protein (MBP), Proteolipid Protein (PLP), and/or Myelin Oligodendrocyte glycoprotein (MOG)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Il1atm1Yiw/Il1atm1Yiw,Il1btm1Yiw/Il1btm1Yiw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004824 decreased susceptibility to experimental autoimmune myasthenia gravis "reduced likelihood that an organism will develop disease symptoms similar to human myasthenia gravis upon induction with antigens to acetylcholine receptor subunits" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

 MP:0004883 abnormal blood vessel healing "anomaly in the repair process of blood vessels after injury" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Spictm1Kmm/Spictm1Kmm
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0005087 reduced acute inflammation "less than the expected early reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into extravascular tissues; initiated by injury, infection, or local immune response " [Pathology:ISBN 0-397-51047-0, J:74478]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

 MP:0005166 decreased susceptiblity to injury "less than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ifngr1tm1Agt/Ifngr1tm1Agt,Tg(GZMB-Tax)#Lera/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Il1btm1Lvp/Il1btm1Lvp
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * C57BL/10 * RIIIS

 MP:0005167 abnormal blood-brain barrier "anomaly in the structure or function of the group of barriers and transport systems in the brain capillary endothelium that controls the entrance of substances into the brain extracellular space from the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Lck-cre)I57Jxm/0
Genetic Background: involves: 129 * 129S6/SvEvTac * C57BL/6 * ICR

 MP:0005616 decreased susceptibility to type IV hypersensitivity reaction "less likelihood of or resistance to developing an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact" [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Muc2M1Btlr/Muc2+
Genetic Background: C57BL/6J-Muc2M1Btlr

Allelic Composition: Il1atm1Yiw/Il1atm1Yiw,Il1btm1Yiw/Il1btm1Yiw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008561 decreased tumor necrosis factor secretion "reduction in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800]
Show

Allelic Composition: Ifngr1tm1Agt/Ifngr1tm1Agt,Tg(GZMB-Tax)#Lera/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008567 decreased interferon-gamma secretion "reduction in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

 MP:0008639 decreased circulating interleukin-1 alpha level "reduction in the amount in the blood of an interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form; both membrane-bound and secreted forms of interleukin-1alpha are biologically active" [MESH:D12.644.276.374.465.501.300]
Show

Allelic Composition: Il1atm1Yiw/Il1atm1Yiw,Il1btm1Yiw/Il1btm1Yiw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008642 decreased circulating interleukin-1 beta level "reduction in the amount in the blood of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes, macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane" [MESH:D12.644.276.374.465.501.600]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

Allelic Composition: Il1btm1Yiw/Il1btm1Yiw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Il1atm1Yiw/Il1atm1Yiw,Il1btm1Yiw/Il1btm1Yiw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008658 decreased interleukin-1 beta secretion "reduction in the production or release of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes, macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane" [MESH:D12.644.276.374.465.501.600]
Show

Allelic Composition: Muc2M1Btlr/Muc2+
Genetic Background: C57BL/6J-Muc2M1Btlr

Allelic Composition: Il1btm1Lvp/Il1btm1Lvp
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008688 decreased interleukin-2 secretion "reduction in the production or release of a soluble substance elaborated by antigen- or mitogen-stimulated T-cells which induces DNA synthesis in naive lymphocytes" [MESH:D12.644.276.374.465.502]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

 MP:0008700 decreased interleukin-4 secretion "reduction in the production or release of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells" [MESH:D12.644.276.374.465.504]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

 MP:0008704 abnormal interleukin-6 secretion "anomaly in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts" [MESH:D12.644.276.374.465.506]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

 MP:0008719 impaired neutrophil recruitment "reduced diffusion or accumulation of neutrophils in tissues or cells in response to a wide variety of substances released at the sites of inflammatory reactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Casp1tm1Sesh/Casp1tm1Sesh,Casp4del/Casp4del
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

 MP:0008831 abnormal insulin-like growth factor I level "aomaly in the concentration of this polypeptide hormone with growth-regulating, insulin-like, and mitogenic activities" [MESH:D12.644.276.937.400, MGI:mberry "Melissa Berry, Genetics Resources Curator"]
Show

Allelic Composition: Muc2M1Btlr/Muc2+
Genetic Background: C57BL/6J-Muc2M1Btlr

 MP:0009764 decreased sensitivity to induced morbidity/mortality "increase in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

Allelic Composition: Il1btm1Lvp/Il1btm1Lvp
Genetic Background: involves: 129S7/SvEvBrd

 MP:0009788 increased susceptibility to bacterial infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Il1btm1Lvp/Il1btm1Lvp
Genetic Background: involves: 129S7/SvEvBrd

 MP:0009790 decreased susceptibility to viral infection induced morbidity/mortality "reduced likelihood that an organism will display the expected moribund state caused by a viral invasion or from components of or toxins produced by a virus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Il1btm1Lvp/Il1btm1Lvp
Genetic Background: involves: 129S7/SvEvBrd

 MP:0010144 abnormal tumor vascularization "aberrant process of blood vessel formation and the subsequent remodeling process within and/or around tumors" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Il1btm1Lvp/Il1btm1Lvp
Genetic Background: involves: 129S7/SvEvBrd

 MP:0030524 abnormal tooth root resorption "pathologic resorption in which cementum or dentin is lost from the root of a tooth owing to cementoclastic or osteoclastic activity in conditions such as trauma of occlusion or neoplasms" [MESH:D012391]
Show

Allelic Composition: Oca2p-25H/Oca2p-25H
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025139 Q9QZ06 / Tollip / toll interacting protein / Q9H0E2*  / reaction / complex
 ENSMUSG00000026029 Casp8 / O89110 / Caspase-8 Caspase-8 subunit p18 Caspase-8 subunit p10 / Q14790* / caspase 8*  / reaction
 ENSMUSG00000026072 Il1r1 / P13504 / Interleukin-1 receptor type 1 Interleukin-1 receptor type 1, membrane form Interleukin-1 receptor type 1, soluble form / P14778* / interleukin 1 receptor type 1*  / complex / reaction
 ENSMUSG00000025888 Casp1 / P29452 / Caspase-1 Caspase-1 subunit p20 Caspase-1 subunit p10 / P29466* / caspase 1*  / reaction
 ENSMUSG00000026073 Il1r2 / P27931 / Interleukin-1 receptor type 2 Interleukin-1 receptor type 2, membrane form Interleukin-1 receptor type 2, soluble form / P27930* / interleukin 1 receptor type 2*  / reaction / complex
 ENSMUSG00000059883 Irak4 / Q8R4K2 / Interleukin-1 receptor-associated kinase 4 / Q9NWZ3*  / reaction / complex
 ENSMUSG00000022514 Il1rap / Q61730 / Interleukin-1 receptor accessory protein / Q9NPH3*  / complex / reaction
 ENSMUSG00000027164 Traf6 / P70196 / TNF receptor-associated factor 6 / Q9Y4K3*  / reaction / complex
 ENSMUSG00000032508 Myd88 / P22366 / myeloid differentiation primary response gene 88 / Q99836* / myeloid differentiation primary response 88*  / complex / reaction
 ENSMUSG00000031392 Irak1 / Q62406 / Interleukin-1 receptor-associated kinase 1 / P51617*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr