ENSGALG00000029940


Gallus gallus

Features
Gene ID: ENSGALG00000029940
  
Biological name :IL1B
  
Synonyms : IL1B / interleukin 1 beta
  
Possible biological names infered from orthology : P01584 / P10749
  
Species: Gallus gallus
  
Chr. number: 22
Strand: -1
Band:
Gene start: 4616890
Gene end: 4618940
  
Corresponding Affymetrix probe sets: Gga.19.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050171
Ensembl peptide - ENSGALP00000047706
NCBI entrez gene - 395196     See in Manteia.
RefSeq - XM_015297469
RefSeq - NM_204524
RefSeq Peptide - NP_989855
swissprot - O73909
swissprot - A0A1D5P4U4
Ensembl - ENSGALG00000029940
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il1bENSDARG00000098700Danio rerio
 IL1BENSG00000125538Homo sapiens
 Il1bENSMUSG00000027398Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000975  Interleukin-1 family
 IPR003296  Interleukin-1 beta
 IPR003502  Interleukin-1 propeptide
 IPR008996  Cytokine IL1/FGF
 IPR020877  Interleukin-1 conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001660 fever generation IEA
 biological_processGO:0002224 toll-like receptor signaling pathway TAS
 biological_processGO:0002232 leukocyte chemotaxis involved in inflammatory response TAS
 biological_processGO:0002269 leukocyte activation involved in inflammatory response TAS
 biological_processGO:0006953 acute-phase response ISS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0009615 response to virus IEP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019953 sexual reproduction TAS
 biological_processGO:0032497 detection of lipopolysaccharide TAS
 biological_processGO:0032602 chemokine production TAS
 biological_processGO:0043400 cortisol secretion IDA
 biological_processGO:0050729 positive regulation of inflammatory response TAS
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0070417 cellular response to cold IEP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005149 interleukin-1 receptor binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-1 processing
Interleukin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001049 CASP1* / CASP4* / CASP5* / Q6UXS9* / CASP12* / O08736* / P29452* / P29466* / P49662* / P51878* / P70343* / caspase 4* / caspase 1* / caspase 5* / Caspase-12 * / caspase 12 (gene/pseudogene)...  / reaction
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSGALG00000009586 IRAK4 / interleukin-1 receptor-associated kinase 4 / Q8R4K2* / Q9NWZ3*  / complex / reaction
 ENSGALG00000005947 MYD88 / A5HNF6 / Myeloid differentiation primary response protein MyD88 / Q99836* / P22366* / myeloid differentiation primary response 88* / myeloid differentiation primary response gene 88*  / reaction / complex
 ENSGALG00000043044 IL1R1 / interleukin-1 receptor type 1 precursor / P14778* / P13504* / interleukin 1 receptor type 1* / Interleukin-1 receptor type 1 Interleukin-1 receptor type 1, membrane form Interleuki...  / reaction / complex
 ENSGALG00000007253 IL1RAP / interleukin 1 receptor accessory protein / Q61730* / Q9NPH3*  / reaction / complex
 ENSGALG00000030526 IL1R1* / P13504* / P14778* / interleukin 1 receptor type 1* / Interleukin-1 receptor type 1 Interleukin-1 receptor type 1, membrane form Interleukin-1 receptor type 1, soluble form*  / reaction / complex






 

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