ENSGALG00000001049


Gallus gallus

Features
Gene ID: ENSGALG00000001049
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : CASP1 / CASP12 / CASP4 / CASP5 / caspase 1 / Caspase-12 / caspase 12 (gene/pseudogene) / Caspase-1 Caspase-1 subunit p20 Caspase-1 subunit p10 / caspase 4 / Caspase-4 Caspase-4 subunit p10 Caspase-4 subunit p20 / caspase 5 / O08736 / P29452 / P29466 / P49662 / P51878 / P70343 / Q6UXS9
  
Species: Gallus gallus
  
Chr. number: 19
Strand: 1
Band:
Gene start: 657606
Gene end: 667042
  
Corresponding Affymetrix probe sets: Gga.10204.1.S1_s_at (Chicken Array)   Gga.1747.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045225
Ensembl peptide - ENSGALP00000061095
Ensembl peptide - ENSGALP00000053981
Ensembl peptide - ENSGALP00000048609
Ensembl peptide - ENSGALP00000001569
NCBI entrez gene - 395764     See in Manteia.
RefSeq - XM_003642384
RefSeq - XM_015295935
swissprot - A0A1L1RQM6
swissprot - A0A1D5PMA6
swissprot - A0A1D5NXX2
swissprot - F1P0X7
Ensembl - ENSGALG00000001049
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 caspaENSDARG00000008165Danio rerio
 caspbENSDARG00000052039Danio rerio
 caspblENSDARG00000094433Danio rerio
 zgc:171731ENSDARG00000014657Danio rerio
 CASP1ENSG00000137752Homo sapiens
 CASP12ENSG00000204403Homo sapiens
 CASP4ENSG00000196954Homo sapiens
 CASP5ENSG00000137757Homo sapiens
 Casp1ENSMUSG00000025888Mus musculus
 Casp12ENSMUSG00000025887Mus musculus
 Casp4ENSMUSG00000033538Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001309  Peptidase C14, p20 domain
 IPR001315  CARD domain
 IPR002138  Peptidase C14, caspase non-catalytic subunit p10
 IPR011029  Death-like domain superfamily
 IPR015917  Peptidase C14A, caspase catalytic domain
 IPR016129  Peptidase family C14A, His active site
 IPR029030  Caspase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0050727 regulation of inflammatory response IBA
 cellular_componentGO:0072557 IPAF inflammasome complex IBA
 cellular_componentGO:0072559 NLRP3 inflammasome complex IBA
 cellular_componentGO:0097169 AIM2 inflammasome complex IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA


Pathways (from Reactome)
Pathway description
NOD1/2 Signaling Pathway
Interleukin-1 processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001049 CASP1* / CASP4* / CASP5* / Q6UXS9* / CASP12* / O08736* / P29452* / P29466* / P49662* / P51878* / P70343* / caspase 4* / caspase 1* / caspase 5* / Caspase-12 * / caspase 12 (gene/pseudogene)...  / complex / reaction
 ENSGALG00000029940 IL1B / interleukin 1 beta / P01584* / P10749*  / reaction






 

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