ENSG00000204403


Homo sapiens

Features
Gene ID: ENSG00000204403
  
Biological name :CASP12
  
Synonyms : CASP12 / caspase 12 (gene/pseudogene) / Q6UXS9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q22.3
Gene start: 104885718
Gene end: 104898670
  
Corresponding Affymetrix probe sets: 1564736_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427437
Ensembl peptide - ENSP00000482745
Ensembl peptide - ENSP00000421408
Ensembl peptide - ENSP00000421815
Ensembl peptide - ENSP00000423899
Ensembl peptide - ENSP00000423970
Ensembl peptide - ENSP00000424038
Ensembl peptide - ENSP00000424963
Ensembl peptide - ENSP00000425652
Ensembl peptide - ENSP00000426427
Ensembl peptide - ENSP00000426566
Ensembl peptide - ENSP00000427128
NCBI entrez gene - 100506742     See in Manteia.
OMIM - 608633
RefSeq - NM_001191016
RefSeq Peptide - NP_001177945
swissprot - Q6UXS9
Ensembl - ENSG00000204403
  
Related genetic diseases (OMIM): 608633 - {Sepsis, susceptibility to}
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 caspaENSDARG00000008165Danio rerio
 caspbENSDARG00000052039Danio rerio
 caspblENSDARG00000094433Danio rerio
 zgc:171731ENSDARG00000014657Danio rerio
 ENSGALG00000001049Gallus gallus
 Casp12ENSMUSG00000025887Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CASP4 / P49662 / caspase 4ENSG0000019695450
CASP5 / P51878 / caspase 5ENSG0000013775747
CASP1 / P29466 / caspase 1ENSG0000013775243


Protein motifs (from Interpro)
Interpro ID Name
 IPR001309  Peptidase C14, p20 domain
 IPR001315  CARD domain
 IPR002138  Peptidase C14, caspase non-catalytic subunit p10
 IPR011029  Death-like domain superfamily
 IPR015917  Peptidase C14A, caspase catalytic domain
 IPR029030  Caspase-like domain superfamily
 IPR033139  Peptidase family C14A, cysteine active site
 IPR035713  Caspase-12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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