ENSDARG00000098700


Danio rerio

Features
Gene ID: ENSDARG00000098700
  
Biological name :il1b
  
Synonyms : il1b / interleukin 1, beta
  
Possible biological names infered from orthology : P01584 / P10749
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 44955106
Gene end: 44964776
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000154078
Ensembl peptide - ENSDARP00000154758
Ensembl peptide - ENSDARP00000140751
NCBI entrez gene - 405770     See in Manteia.
RefSeq - NM_212844
RefSeq Peptide - NP_998009
swissprot - A0A0R4IYF1
ZFIN ID - ZDB-GENE-040702-2
Ensembl - ENSDARG00000098700
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL1BENSGALG00000029940Gallus gallus
 IL1BENSG00000125538Homo sapiens
 Il1bENSMUSG00000027398Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000975  Interleukin-1 family
 IPR008996  Cytokine IL1/FGF
 IPR020877  Interleukin-1 conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002237 response to molecule of bacterial origin IDA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response IDA
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0009617 response to bacterium IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IMP
 biological_processGO:0031101 fin regeneration IMP
 biological_processGO:0032496 response to lipopolysaccharide IDA
 biological_processGO:0042119 neutrophil activation IMP
 biological_processGO:0042742 defense response to bacterium IDA
 biological_processGO:0043330 response to exogenous dsRNA IDA
 biological_processGO:0046685 response to arsenic-containing substance IDA
 biological_processGO:0048246 macrophage chemotaxis IMP
 biological_processGO:1901222 regulation of NIK/NF-kappaB signaling IGI
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005149 interleukin-1 receptor binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-1 processing
CLEC7A/inflammasome pathway
Interleukin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord neutrophil activation involved in immune response decreased occurrence , abnormal
notochord neutrophil decreased amount , abnormal
Show

 ZFA:0001058 caudal fin caudal fin regenerating fin decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased life span , exacerbated
Show

 ZFA:0001269 regenerating fin regenerating fin decreased length , abnormal
regenerating fin cell proliferation decreased occurrence , abnormal
Show

 ZFA:0009327 neutrophil neutrophil decreased amount , abnormal
neutrophil decreased velocity , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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