16337


Mus musculus (NCBI)

Features
Gene ID: 16337
  
Biological name :
  
Synonyms : 4932439J01Rik|CD220|D630014A15Rik|IR|IR-A|IR-B / Insr / insulin receptor
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421380_at (Mouse Genome 430 2.0 Array)   1434446_at (Mouse Genome 430 2.0 Array)   1450225_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_006508764.1
RefSeq - 157057178
RefSeq - 568953120
RefSeq - 568953122
RefSeq - 568953124
RefSeq - NC_000074.6
RefSeq - NP_001316985.1
RefSeq - NP_034698.2
RefSeq - XP_006508762.1
RefSeq - XP_006508763.1
RefSeq - 1052292402
RefSeq - NM_001330056.1
RefSeq - NM_010568.3
RefSeq - XM_006508700.1
RefSeq - XM_006508701.1
RefSeq - XM_006508699.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000005534 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity ISO
 biological_processGO:0001933 negative regulation of protein phosphorylation ISO
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0003007 heart morphogenesis ISO
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008286 insulin receptor signaling pathway ISO
 biological_processGO:0008544 epidermis development IMP
 biological_processGO:0008584 male gonad development IGI
 biological_processGO:0009887 animal organ morphogenesis IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010310 regulation of hydrogen peroxide metabolic process ISO
 biological_processGO:0010560 positive regulation of glycoprotein biosynthetic process ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0019087 transformation of host cell by virus ISO
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030238 male sex determination IMP
 biological_processGO:0030325 adrenal gland development IGI
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0032147 activation of protein kinase activity ISO
 biological_processGO:0032148 activation of protein kinase B activity ISO
 biological_processGO:0032410 negative regulation of transporter activity ISO
 biological_processGO:0032869 cellular response to insulin stimulus ISO
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0034612 response to tumor necrosis factor ISO
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IDA
 biological_processGO:0042327 positive regulation of phosphorylation ISO
 biological_processGO:0042593 glucose homeostasis ISO
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043243 positive regulation of protein complex disassembly ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process ISO
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process ISO
 biological_processGO:0045821 positive regulation of glycolytic process ISO
 biological_processGO:0045840 positive regulation of mitotic nuclear division ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IGI
 biological_processGO:0045995 regulation of embryonic development ISO
 biological_processGO:0046326 positive regulation of glucose import ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048639 positive regulation of developmental growth ISO
 biological_processGO:0051290 protein heterotetramerization ISO
 biological_processGO:0051446 positive regulation of meiotic cell cycle IGI
 biological_processGO:0051897 positive regulation of protein kinase B signaling ISO
 biological_processGO:0060267 positive regulation of respiratory burst ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071363 cellular response to growth factor stimulus IDA
 biological_processGO:0097062 dendritic spine maintenance ISO
 biological_processGO:0097242 amyloid-beta clearance ISO
 biological_processGO:1990535 neuron projection maintenance ISO
 biological_processGO:2000194 regulation of female gonad development IGI
 cellular_componentGO:0005622 intracellular ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005635 nuclear envelope ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005768 endosome ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0005899 insulin receptor complex ISO
 cellular_componentGO:0005901 caveola ISO
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IBA
 cellular_componentGO:0031981 nuclear lumen ISO
 cellular_componentGO:0032590 dendrite membrane ISO
 cellular_componentGO:0032809 neuronal cell body membrane ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0043235 receptor complex ISO
 cellular_componentGO:0045202 synapse ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001540 amyloid-beta binding ISO
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005009 insulin-activated receptor activity ISO
 molecular_functionGO:0005159 insulin-like growth factor receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0005525 GTP binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019903 protein phosphatase binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0031405 lipoic acid binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0031994 insulin-like growth factor I binding ISO
 molecular_functionGO:0031995 insulin-like growth factor II binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0043423 3-phosphoinositide-dependent protein kinase binding ISO
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding ISO
 molecular_functionGO:0043559 insulin binding ISO
 molecular_functionGO:0043560 insulin receptor substrate binding ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0051425 PTB domain binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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