16367


Mus musculus (NCBI)

Features
Gene ID: 16367
  
Biological name :
  
Synonyms : G972R|IRS-1 / insulin receptor substrate 1 / Irs1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1423104_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 29825829
RefSeq - NC_000067.6
RefSeq - NP_034700.2
RefSeq - NM_010570.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000055980 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IGI
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008286 insulin receptor signaling pathway ISO
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0010907 positive regulation of glucose metabolic process ISO
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016042 lipid catabolic process IMP
 biological_processGO:0019216 regulation of lipid metabolic process IBA
 biological_processGO:0030073 insulin secretion IMP
 biological_processGO:0030335 positive regulation of cell migration IGI
 biological_processGO:0030879 mammary gland development IGI
 biological_processGO:0031000 response to caffeine ISO
 biological_processGO:0032000 positive regulation of fatty acid beta-oxidation ISO
 biological_processGO:0032868 response to insulin ISO
 biological_processGO:0032869 cellular response to insulin stimulus ISO
 biological_processGO:0034504 protein localization to nucleus IMP
 biological_processGO:0042327 positive regulation of phosphorylation ISO
 biological_processGO:0043434 response to peptide hormone ISO
 biological_processGO:0043491 protein kinase B signaling IGI
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity ISO
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process ISO
 biological_processGO:0046326 positive regulation of glucose import ISO
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway ISO
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway ISO
 biological_processGO:0046676 negative regulation of insulin secretion ISO
 biological_processGO:0048009 insulin-like growth factor receptor signaling pathway ISO
 biological_processGO:0051291 protein heterooligomerization ISO
 biological_processGO:0070094 positive regulation of glucagon secretion ISO
 biological_processGO:0090275 negative regulation of somatostatin secretion ISO
 biological_processGO:1904385 cellular response to angiotensin ISO
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005899 insulin receptor complex ISO
 cellular_componentGO:0005901 caveola ISO
 cellular_componentGO:0036064 ciliary basal body IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0001784 phosphotyrosine residue binding ISO
 molecular_functionGO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity ISO
 molecular_functionGO:0005080 protein kinase C binding ISO
 molecular_functionGO:0005158 insulin receptor binding ISO
 molecular_functionGO:0005159 insulin-like growth factor receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0042169 SH2 domain binding ISO
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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