16396


Mus musculus (NCBI)

Features
Gene ID: 16396
  
Biological name :
  
Synonyms : 6720481N21Rik|8030492O04Rik|A130065M08|AIP4|C230047C07Rik / Itch / itchy, E3 ubiquitin protein ligase
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1415769_at (Mouse Genome 430 2.0 Array)   1431316_at (Mouse Genome 430 2.0 Array)   1440582_at (Mouse Genome 430 2.0 Array)   1459332_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_001230641.1
RefSeq - NP_032421.2
RefSeq - 343962614
RefSeq - 124487317
RefSeq - NC_000068.7
RefSeq - XR_001781069.1
RefSeq - NM_001243712.1
RefSeq - NM_008395.3
RefSeq - XR_001781068.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000027598 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002669 positive regulation of T cell anergy IMP
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process ISO
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0035519 protein K29-linked ubiquitination ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IMP
 biological_processGO:0046329 negative regulation of JNK cascade IMP
 biological_processGO:0046642 negative regulation of alpha-beta T cell proliferation IMP
 biological_processGO:0050687 negative regulation of defense response to virus ISO
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0051865 protein autoubiquitination ISO
 biological_processGO:0070534 protein K63-linked ubiquitination ISO
 biological_processGO:0070936 protein K48-linked ubiquitination ISO
 biological_processGO:0090085 regulation of protein deubiquitination IMP
 biological_processGO:2000646 positive regulation of receptor catabolic process ISO
 cellular_componentGO:0000151 ubiquitin ligase complex ISA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016874 ligase activity IMP
 molecular_functionGO:0043021 ribonucleoprotein complex binding ISO
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding ISO
 molecular_functionGO:0045236 CXCR chemokine receptor binding ISO
 molecular_functionGO:0061630 ubiquitin protein ligase activity ISO
 molecular_functionGO:1990763 arrestin family protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr