16542


Mus musculus (NCBI)

Features
Gene ID: 16542
  
Biological name :
  
Synonyms : 6130401C07|Flk-1|Flk1|Krd-1|Ly73|VEGFR-2|VEGFR2|orv|sVEGFR-2 / Kdr / kinase insert domain protein receptor
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1449379_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1388591307
RefSeq - 27777648
RefSeq - 755512111
RefSeq - NC_000071.6
RefSeq - NP_001350145.1
RefSeq - NP_034742.2
RefSeq - XP_011239119.1
RefSeq - NM_001363216.1
RefSeq - NM_010612.3
RefSeq - XM_011240817.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000062960 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0001936 regulation of endothelial cell proliferation TAS
 biological_processGO:0001938 positive regulation of endothelial cell proliferation ISO
 biological_processGO:0001945 lymph vessel development IGI
 biological_processGO:0002042 cell migration involved in sprouting angiogenesis IMP
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IMP
 biological_processGO:0003157 endocardium development IMP
 biological_processGO:0003158 endothelium development IMP
 biological_processGO:0003416 endochondral bone growth ISO
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration ISO
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008360 regulation of cell shape ISO
 biological_processGO:0008584 male gonad development ISO
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010595 positive regulation of endothelial cell migration TAS
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016239 positive regulation of macroautophagy ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IGI
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030324 lung development IMP
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030513 positive regulation of BMP signaling pathway IDA
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0032008 positive regulation of TOR signaling ISO
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035162 embryonic hemopoiesis IMP
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source ISO
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus ISO
 biological_processGO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway ISO
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IDA
 biological_processGO:0042493 response to drug ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043129 surfactant homeostasis IMP
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0043491 protein kinase B signaling ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0045165 cell fate commitment IMP
 biological_processGO:0045446 endothelial cell differentiation TAS
 biological_processGO:0045601 regulation of endothelial cell differentiation IMP
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway ISO
 biological_processGO:0048170 positive regulation of long-term neuronal synaptic plasticity ISO
 biological_processGO:0048286 lung alveolus development IMP
 biological_processGO:0048469 cell maturation IMP
 biological_processGO:0048597 post-embryonic camera-type eye morphogenesis IGI
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IMP
 biological_processGO:0048812 neuron projection morphogenesis ISO
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IMP
 biological_processGO:0050850 positive regulation of calcium-mediated signaling ISO
 biological_processGO:0050927 positive regulation of positive chemotaxis ISO
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process ISO
 biological_processGO:0051894 positive regulation of focal adhesion assembly ISO
 biological_processGO:0051901 positive regulation of mitochondrial depolarization ISO
 biological_processGO:0055074 calcium ion homeostasis IDA
 biological_processGO:0060837 blood vessel endothelial cell differentiation TAS
 biological_processGO:0070371 ERK1 and ERK2 cascade ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis ISO
 biological_processGO:0090141 positive regulation of mitochondrial fission ISO
 biological_processGO:0097755 positive regulation of blood vessel diameter ISO
 biological_processGO:1901532 regulation of hematopoietic progenitor cell differentiation IMP
 biological_processGO:1903010 regulation of bone development IMP
 biological_processGO:1904881 cellular response to hydrogen sulfide ISO
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process ISO
 biological_processGO:2001214 positive regulation of vasculogenesis IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005768 endosome ISO
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0071944 cell periphery IDA
 cellular_componentGO:0097443 sorting endosome IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity ISO
 molecular_functionGO:0005178 integrin binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038085 vascular endothelial growth factor binding ISO
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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