16835


Mus musculus (NCBI)

Features
Gene ID: 16835
  
Biological name :
  
Synonyms : Hlb301 / Ldlr / low density lipoprotein receptor
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421821_at (Mouse Genome 430 2.0 Array)   1431947_at (Mouse Genome 430 2.0 Array)   1450383_at (Mouse Genome 430 2.0 Array)   1459403_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 113195700
RefSeq - 358030301
RefSeq - 358030304
RefSeq - NC_000075.6
RefSeq - NP_001239587.1
RefSeq - NP_001239588.1
RefSeq - NP_034830.2
RefSeq - NM_001252658.1
RefSeq - NM_001252659.1
RefSeq - NM_010700.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000032193 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IGI
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0006897 endocytosis ISO
 biological_processGO:0006898 receptor-mediated endocytosis IDA
 biological_processGO:0007616 long-term memory ISO
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008203 cholesterol metabolic process IMP
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0010867 positive regulation of triglyceride biosynthetic process IMP
 biological_processGO:0010898 positive regulation of triglyceride catabolic process ISO
 biological_processGO:0010899 regulation of phosphatidylcholine catabolic process IMP
 biological_processGO:0010986 positive regulation of lipoprotein particle clearance IDA
 biological_processGO:0015914 phospholipid transport IMP
 biological_processGO:0030299 intestinal cholesterol absorption ISO
 biological_processGO:0030301 cholesterol transport ISO
 biological_processGO:0034383 low-density lipoprotein particle clearance ISO
 biological_processGO:0042157 lipoprotein metabolic process IGI
 biological_processGO:0042159 lipoprotein catabolic process IMP
 biological_processGO:0042632 cholesterol homeostasis ISO
 biological_processGO:0045807 positive regulation of endocytosis IDA
 biological_processGO:0050729 positive regulation of inflammatory response IGI
 biological_processGO:0051246 regulation of protein metabolic process ISO
 biological_processGO:0051248 negative regulation of protein metabolic process IDA
 biological_processGO:0061771 response to caloric restriction ISO
 biological_processGO:0061889 negative regulation of astrocyte activation IGI
 biological_processGO:0070508 cholesterol import ISO
 biological_processGO:0071398 cellular response to fatty acid IGI
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus ISO
 biological_processGO:0090118 receptor-mediated endocytosis involved in cholesterol transport ISO
 biological_processGO:0090181 regulation of cholesterol metabolic process IGI
 biological_processGO:0097242 amyloid-beta clearance IDA
 biological_processGO:1900223 positive regulation of amyloid-beta clearance IGI
 biological_processGO:1903979 negative regulation of microglial cell activation IGI
 biological_processGO:1905167 positive regulation of lysosomal protein catabolic process IDA
 biological_processGO:1905907 negative regulation of amyloid fibril formation IGI
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005770 late endosome ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005901 caveola ISO
 cellular_componentGO:0005905 clathrin-coated pit ISO
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0034362 low-density lipoprotein particle IEA
 cellular_componentGO:0036477 somatodendritic compartment IDA
 cellular_componentGO:0043235 receptor complex ISO
 cellular_componentGO:0045177 apical part of cell IDA
 cellular_componentGO:0055038 recycling endosome membrane ISO
 cellular_componentGO:0097443 sorting endosome IDA
 cellular_componentGO:1990666 PCSK9-LDLR complex ISO
 molecular_functionGO:0001540 amyloid-beta binding IPI
 molecular_functionGO:0002020 protease binding ISO
 molecular_functionGO:0005041 low-density lipoprotein particle receptor activity ISO
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030169 low-density lipoprotein particle binding ISO
 molecular_functionGO:0030229 very-low-density lipoprotein particle receptor activity ISO
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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