16846


Mus musculus (NCBI)

Features
Gene ID: 16846
  
Biological name :
  
Synonyms : Lep / leptin / ob|obese
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422582_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6678678
RefSeq - XP_006505062.1
RefSeq - NC_000072.6
RefSeq - 568939447
RefSeq - NP_032519.1
RefSeq - NM_008493.3
RefSeq - XM_006504999.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000059201 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001525 angiogenesis ISO
 biological_processGO:0001542 ovulation from ovarian follicle ISO
 biological_processGO:0001890 placenta development ISO
 biological_processGO:0001932 regulation of protein phosphorylation IDA
 biological_processGO:0001936 regulation of endothelial cell proliferation ISO
 biological_processGO:0002021 response to dietary excess ISO
 biological_processGO:0003300 cardiac muscle hypertrophy ISO
 biological_processGO:0006006 glucose metabolic process IMP
 biological_processGO:0006111 regulation of gluconeogenesis IMP
 biological_processGO:0006112 energy reserve metabolic process ISO
 biological_processGO:0006114 glycerol biosynthetic process ISO
 biological_processGO:0006629 lipid metabolic process IMP
 biological_processGO:0006635 fatty acid beta-oxidation IGI
 biological_processGO:0006909 phagocytosis ISO
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007260 tyrosine phosphorylation of STAT protein IDA
 biological_processGO:0008203 cholesterol metabolic process IGI
 biological_processGO:0008206 bile acid metabolic process IDA
 biological_processGO:0008217 regulation of blood pressure ISO
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008343 adult feeding behavior IDA
 biological_processGO:0009062 fatty acid catabolic process ISO
 biological_processGO:0009892 negative regulation of metabolic process ISO
 biological_processGO:0010507 negative regulation of autophagy ISO
 biological_processGO:0010888 negative regulation of lipid storage ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0019222 regulation of metabolic process IMP
 biological_processGO:0019953 sexual reproduction ISO
 biological_processGO:0021954 central nervous system neuron development IMP
 biological_processGO:0030073 insulin secretion IGI
 biological_processGO:0030217 T cell differentiation IMP
 biological_processGO:0030300 regulation of intestinal cholesterol absorption IDA
 biological_processGO:0032008 positive regulation of TOR signaling ISO
 biological_processGO:0032099 negative regulation of appetite IDA
 biological_processGO:0032310 prostaglandin secretion ISO
 biological_processGO:0032615 interleukin-12 production IDA
 biological_processGO:0032635 interleukin-6 production IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IDA
 biological_processGO:0032814 regulation of natural killer cell activation ISO
 biological_processGO:0032817 regulation of natural killer cell proliferation ISO
 biological_processGO:0032868 response to insulin IMP
 biological_processGO:0033210 leptin-mediated signaling pathway ISO
 biological_processGO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway ISO
 biological_processGO:0035556 intracellular signal transduction ISO
 biological_processGO:0035630 bone mineralization involved in bone maturation ISO
 biological_processGO:0038108 negative regulation of appetite by leptin-mediated signaling pathway ISO
 biological_processGO:0042102 positive regulation of T cell proliferation ISO
 biological_processGO:0042269 regulation of natural killer cell mediated cytotoxicity ISO
 biological_processGO:0042307 positive regulation of protein import into nucleus IDA
 biological_processGO:0042445 hormone metabolic process IMP
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISO
 biological_processGO:0042593 glucose homeostasis IGI
 biological_processGO:0042755 eating behavior IGI
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043270 positive regulation of ion transport ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0044320 cellular response to leptin stimulus ISO
 biological_processGO:0045598 regulation of fat cell differentiation IGI
 biological_processGO:0045639 positive regulation of myeloid cell differentiation IDA
 biological_processGO:0045765 regulation of angiogenesis ISO
 biological_processGO:0045906 negative regulation of vasoconstriction ISO
 biological_processGO:0046325 negative regulation of glucose import ISO
 biological_processGO:0046427 positive regulation of JAK-STAT cascade ISO
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway ISO
 biological_processGO:0046850 regulation of bone remodeling IMP
 biological_processGO:0048639 positive regulation of developmental growth ISO
 biological_processGO:0050796 regulation of insulin secretion IMP
 biological_processGO:0050810 regulation of steroid biosynthetic process IMP
 biological_processGO:0050892 intestinal absorption ISO
 biological_processGO:0050901 leukocyte tethering or rolling ISO
 biological_processGO:0050999 regulation of nitric-oxide synthase activity ISO
 biological_processGO:0051726 regulation of cell cycle ISO
 biological_processGO:0051897 positive regulation of protein kinase B signaling IDA
 biological_processGO:0060587 regulation of lipoprotein lipid oxidation ISO
 biological_processGO:0060612 adipose tissue development IGI
 biological_processGO:0061037 negative regulation of cartilage development ISO
 biological_processGO:0070093 negative regulation of glucagon secretion IDA
 biological_processGO:0072604 interleukin-6 secretion ISO
 biological_processGO:0072606 interleukin-8 secretion ISO
 biological_processGO:0090335 regulation of brown fat cell differentiation IDA
 biological_processGO:0098868 bone growth IMP
 biological_processGO:1900015 regulation of cytokine production involved in inflammatory response ISO
 biological_processGO:1900180 regulation of protein localization to nucleus IMP
 biological_processGO:1900745 positive regulation of p38MAPK cascade ISO
 biological_processGO:1904651 positive regulation of fat cell apoptotic process ISO
 biological_processGO:1990051 activation of protein kinase C activity ISO
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process ISO
 biological_processGO:2000486 negative regulation of glutamine transport ISO
 biological_processGO:2000491 positive regulation of hepatic stellate cell activation ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005179 hormone activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IDA
 molecular_functionGO:0051428 peptide hormone receptor binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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