170744


Mus musculus (NCBI)

Features
Gene ID: 170744
  
Biological name :
  
Synonyms : Tlr8 / toll-like receptor 8
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1450267_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1039796467
RefSeq - 126723495
RefSeq - 569011728
RefSeq - 924181709
RefSeq - 924182698
RefSeq - NC_000086.7
RefSeq - NP_001300689.1
RefSeq - NP_001300690.1
RefSeq - NP_573475.2
RefSeq - XP_006528782.1
RefSeq - XP_017173894.1
RefSeq - NM_001313760.1
RefSeq - NM_001313761.1
RefSeq - NM_133212.3
RefSeq - XM_017318405.1
RefSeq - XM_006528719.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000040522 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001774 microglial cell activation ISO
 biological_processGO:0001932 regulation of protein phosphorylation IGI
 biological_processGO:0002224 toll-like receptor signaling pathway ISO
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway IEA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0009615 response to virus ISO
 biological_processGO:0032755 positive regulation of interleukin-6 production IBA
 biological_processGO:0034158 toll-like receptor 8 signaling pathway ISO
 biological_processGO:0045078 positive regulation of interferon-gamma biosynthetic process ISO
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045089 positive regulation of innate immune response ISO
 biological_processGO:0045356 positive regulation of interferon-alpha biosynthetic process ISO
 biological_processGO:0045359 positive regulation of interferon-beta biosynthetic process ISO
 biological_processGO:0045416 positive regulation of interleukin-8 biosynthetic process ISO
 biological_processGO:0050707 regulation of cytokine secretion IEA
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion ISO
 biological_processGO:0051607 defense response to virus ISO
 biological_processGO:2000778 positive regulation of interleukin-6 secretion ISO
 biological_processGO:2001183 negative regulation of interleukin-12 secretion ISO
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding ISO
 molecular_functionGO:0003727 single-stranded RNA binding ISO
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0008329 signaling pattern recognition receptor activity IBA
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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