17096


Mus musculus (NCBI)

Features
Gene ID: 17096
  
Biological name :
  
Synonyms : AA407514|Hck-2|p53Lyn|p56Lyn / Lyn / LYN proto-oncogene, Src family tyrosine kinase
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1425598_a_at (Mouse Genome 430 2.0 Array)   1451318_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 161760634
RefSeq - 161760636
RefSeq - 755506082
RefSeq - NC_000070.6
RefSeq - NP_001104566.1
RefSeq - NP_034877.2
RefSeq - XP_011248241.1
RefSeq - NM_001111096.1
RefSeq - NM_010747.2
RefSeq - XM_011249939.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000042228 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001782 B cell homeostasis IMP
 biological_processGO:0001817 regulation of cytokine production IMP
 biological_processGO:0001933 negative regulation of protein phosphorylation IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002431 Fc receptor mediated stimulatory signaling pathway IMP
 biological_processGO:0002513 tolerance induction to self antigen IMP
 biological_processGO:0002553 histamine secretion by mast cell ISO
 biological_processGO:0002576 platelet degranulation IMP
 biological_processGO:0002762 negative regulation of myeloid leukocyte differentiation IMP
 biological_processGO:0002768 immune response-regulating cell surface receptor signaling pathway IMP
 biological_processGO:0002774 Fc receptor mediated inhibitory signaling pathway IMP
 biological_processGO:0002902 regulation of B cell apoptotic process IMP
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway ISO
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0009725 response to hormone IDA
 biological_processGO:0010976 positive regulation of neuron projection development ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0030889 negative regulation of B cell proliferation IMP
 biological_processGO:0031175 neuron projection development IMP
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IMP
 biological_processGO:0033003 regulation of mast cell activation IMP
 biological_processGO:0033628 regulation of cell adhesion mediated by integrin ISO
 biological_processGO:0034136 negative regulation of toll-like receptor 2 signaling pathway IMP
 biological_processGO:0034144 negative regulation of toll-like receptor 4 signaling pathway IMP
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042327 positive regulation of phosphorylation ISO
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IMP
 biological_processGO:0042541 hemoglobin biosynthetic process TAS
 biological_processGO:0043304 regulation of mast cell degranulation IMP
 biological_processGO:0043407 negative regulation of MAP kinase activity IMP
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045646 regulation of erythrocyte differentiation IMP
 biological_processGO:0046777 protein autophosphorylation TAS
 biological_processGO:0050663 cytokine secretion ISO
 biological_processGO:0050707 regulation of cytokine secretion IMP
 biological_processGO:0050727 regulation of inflammatory response IMP
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050853 B cell receptor signaling pathway IDA
 biological_processGO:0050855 regulation of B cell receptor signaling pathway IMP
 biological_processGO:0050861 positive regulation of B cell receptor signaling pathway IGI
 biological_processGO:0051272 positive regulation of cellular component movement ISO
 biological_processGO:0051279 regulation of release of sequestered calcium ion into cytosol ISO
 biological_processGO:0060252 positive regulation of glial cell proliferation ISO
 biological_processGO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway ISO
 biological_processGO:0070304 positive regulation of stress-activated protein kinase signaling cascade ISO
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070447 positive regulation of oligodendrocyte progenitor proliferation ISO
 biological_processGO:0070667 negative regulation of mast cell proliferation IMP
 biological_processGO:0070668 positive regulation of mast cell proliferation ISO
 biological_processGO:0071300 cellular response to retinoic acid ISO
 biological_processGO:0090025 regulation of monocyte chemotaxis ISO
 biological_processGO:0090330 regulation of platelet aggregation IMP
 biological_processGO:0097028 dendritic cell differentiation IMP
 biological_processGO:1902532 negative regulation of intracellular signal transduction IMP
 biological_processGO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process ISO
 biological_processGO:2000670 positive regulation of dendritic cell apoptotic process IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005758 mitochondrial intermembrane space ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005913 cell-cell adherens junction ISO
 cellular_componentGO:0014069 postsynaptic density ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0030061 mitochondrial crista ISO
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 cellular_componentGO:0031966 mitochondrial membrane ISO
 cellular_componentGO:0034666 integrin alpha2-beta1 complex ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IBA
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005128 erythropoietin receptor binding TAS
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding ISO
 molecular_functionGO:0005178 integrin binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017124 SH3 domain binding IPI
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0043015 gamma-tubulin binding ISO
 molecular_functionGO:0043208 glycosphingolipid binding ISO
 molecular_functionGO:0044325 ion channel binding ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0046875 ephrin receptor binding ISO
 molecular_functionGO:0051219 phosphoprotein binding ISO
 molecular_functionGO:0140031 phosphorylation-dependent protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr