17127


Mus musculus (NCBI)

Features
Gene ID: 17127
  
Biological name :
  
Synonyms : AU022421|Madh3 / Smad3 / SMAD family member 3
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1450471_at (Mouse Genome 430 2.0 Array)   1450472_s_at (Mouse Genome 430 2.0 Array)   1454960_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_006510884.1
RefSeq - 568960765
RefSeq - 755529748
RefSeq - NC_000075.6
RefSeq - NP_058049.3
RefSeq - XP_006510882.2
RefSeq - 254675249
RefSeq - NM_016769.4
RefSeq - XM_006510821.3
RefSeq - XM_006510819.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000032402 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0001501 skeletal system development IGI
 biological_processGO:0001649 osteoblast differentiation IMP
 biological_processGO:0001657 ureteric bud development IEP
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001701 in utero embryonic development IGI
 biological_processGO:0001707 mesoderm formation IMP
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0001889 liver development IGI
 biological_processGO:0001947 heart looping IGI
 biological_processGO:0002076 osteoblast development IGI
 biological_processGO:0002520 immune system development IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0006955 immune response ISO
 biological_processGO:0007050 cell cycle arrest ISO
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0007183 SMAD protein complex assembly ISO
 biological_processGO:0007369 gastrulation IGI
 biological_processGO:0007492 endoderm development IGI
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0009880 embryonic pattern specification IGI
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010694 positive regulation of alkaline phosphatase activity ISO
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition ISO
 biological_processGO:0016202 regulation of striated muscle tissue development IDA
 biological_processGO:0017015 regulation of transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0019049 evasion or tolerance of host defenses by virus ISO
 biological_processGO:0023019 signal transduction involved in regulation of gene expression ISO
 biological_processGO:0030308 negative regulation of cell growth ISO
 biological_processGO:0030325 adrenal gland development ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030501 positive regulation of bone mineralization ISO
 biological_processGO:0030878 thyroid gland development IGI
 biological_processGO:0032332 positive regulation of chondrocyte differentiation IMP
 biological_processGO:0032731 positive regulation of interleukin-1 beta production ISO
 biological_processGO:0032909 regulation of transforming growth factor beta2 production ISO
 biological_processGO:0032916 positive regulation of transforming growth factor beta3 production ISO
 biological_processGO:0032924 activin receptor signaling pathway ISO
 biological_processGO:0033689 negative regulation of osteoblast proliferation IMP
 biological_processGO:0038092 nodal signaling pathway ISO
 biological_processGO:0042110 T cell activation IMP
 biological_processGO:0042177 negative regulation of protein catabolic process ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0045216 cell-cell junction organization ISO
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process ISO
 biological_processGO:0045599 negative regulation of fat cell differentiation ISO
 biological_processGO:0045668 negative regulation of osteoblast differentiation IGI
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045930 negative regulation of mitotic cell cycle ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048340 paraxial mesoderm morphogenesis IMP
 biological_processGO:0048589 developmental growth IGI
 biological_processGO:0048617 embryonic foregut morphogenesis IGI
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IGI
 biological_processGO:0050678 regulation of epithelial cell proliferation IMP
 biological_processGO:0050728 negative regulation of inflammatory response IMP
 biological_processGO:0050776 regulation of immune response IMP
 biological_processGO:0050821 protein stabilization ISO
 biological_processGO:0050927 positive regulation of positive chemotaxis ISO
 biological_processGO:0051098 regulation of binding IDA
 biological_processGO:0051481 negative regulation of cytosolic calcium ion concentration ISO
 biological_processGO:0051496 positive regulation of stress fiber assembly ISO
 biological_processGO:0051894 positive regulation of focal adhesion assembly ISO
 biological_processGO:0060039 pericardium development IGI
 biological_processGO:0060070 canonical Wnt signaling pathway ISO
 biological_processGO:0060290 transdifferentiation ISO
 biological_processGO:0060395 SMAD protein signal transduction IGI
 biological_processGO:0061045 negative regulation of wound healing IMP
 biological_processGO:0061767 negative regulation of lung blood pressure ISO
 biological_processGO:0070306 lens fiber cell differentiation IMP
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus ISO
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway ISO
 biological_processGO:0097191 extrinsic apoptotic signaling pathway ISO
 biological_processGO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway ISO
 biological_processGO:1901203 positive regulation of extracellular matrix assembly ISO
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II ISO
 biological_processGO:1903243 negative regulation of cardiac muscle hypertrophy in response to stress ISO
 cellular_componentGO:0000790 nuclear chromatin ISO
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005637 nuclear inner membrane ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005667 transcription factor complex ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043235 receptor complex ISO
 cellular_componentGO:0071141 SMAD protein complex ISO
 cellular_componentGO:0071144 heteromeric SMAD protein complex ISO
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding ISO
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0000989 transcription factor activity, transcription factor binding ISO
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding ISO
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IPI
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0005160 transforming growth factor beta receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding IPI
 molecular_functionGO:0008013 beta-catenin binding ISO
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0017151 DEAD/H-box RNA helicase binding ISO
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019902 phosphatase binding ISO
 molecular_functionGO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ISO
 molecular_functionGO:0031490 chromatin DNA binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0031962 mineralocorticoid receptor binding ISO
 molecular_functionGO:0035259 glucocorticoid receptor binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043130 ubiquitin binding ISO
 molecular_functionGO:0043425 bHLH transcription factor binding ISO
 molecular_functionGO:0043565 sequence-specific DNA binding ISO
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISO
 molecular_functionGO:0046332 SMAD binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0070410 co-SMAD binding ISO
 molecular_functionGO:0070412 R-SMAD binding ISO
 molecular_functionGO:0070878 primary miRNA binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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