17128


Mus musculus (NCBI)

Features
Gene ID: 17128
  
Biological name :
  
Synonyms : AW743858|D18Wsu70e|DPC4|Madh4 / Smad4 / SMAD family member 4
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422485_at (Mouse Genome 430 2.0 Array)   1422486_a_at (Mouse Genome 430 2.0 Array)   1422487_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_011245157.1
RefSeq - 569003380
RefSeq - 569003382
RefSeq - 755560583
RefSeq - NC_000084.6
RefSeq - NP_032566.2
RefSeq - XP_006525764.1
RefSeq - XP_006525765.1
RefSeq - 31543224
RefSeq - NM_008540.2
RefSeq - XM_011246855.2
RefSeq - XM_006525701.3
RefSeq - XM_006525702.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000024515 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0001649 osteoblast differentiation ISO
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IGI
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001702 gastrulation with mouth forming second IMP
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0003148 outflow tract septum morphogenesis IGI
 biological_processGO:0003190 atrioventricular valve formation IGI
 biological_processGO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation IMP
 biological_processGO:0003220 left ventricular cardiac muscle tissue morphogenesis IMP
 biological_processGO:0003251 positive regulation of cell proliferation involved in heart valve morphogenesis IMP
 biological_processGO:0003279 cardiac septum development IGI
 biological_processGO:0003360 brainstem development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006879 cellular iron ion homeostasis IMP
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0007183 SMAD protein complex assembly ISO
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0007338 single fertilization IGI
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0007492 endoderm development IMP
 biological_processGO:0007498 mesoderm development IMP
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0008285 negative regulation of cell proliferation IGI
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0008585 female gonad development IGI
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0010614 negative regulation of cardiac muscle hypertrophy IMP
 biological_processGO:0010666 positive regulation of cardiac muscle cell apoptotic process ISO
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IMP
 biological_processGO:0014033 neural crest cell differentiation IMP
 biological_processGO:0017015 regulation of transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0030308 negative regulation of cell growth ISO
 biological_processGO:0030509 BMP signaling pathway ISO
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0030513 positive regulation of BMP signaling pathway ISO
 biological_processGO:0032525 somite rostral/caudal axis specification IMP
 biological_processGO:0032909 regulation of transforming growth factor beta2 production ISO
 biological_processGO:0033686 positive regulation of luteinizing hormone secretion IMP
 biological_processGO:0035556 intracellular signal transduction ISO
 biological_processGO:0036302 atrioventricular canal development IGI
 biological_processGO:0042060 wound healing ISO
 biological_processGO:0042118 endothelial cell activation IMP
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0042177 negative regulation of protein catabolic process ISO
 biological_processGO:0042733 embryonic digit morphogenesis IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046881 positive regulation of follicle-stimulating hormone secretion IMP
 biological_processGO:0048589 developmental growth IMP
 biological_processGO:0048663 neuron fate commitment IMP
 biological_processGO:0048729 tissue morphogenesis IMP
 biological_processGO:0048733 sebaceous gland development IMP
 biological_processGO:0048859 formation of anatomical boundary IMP
 biological_processGO:0051098 regulation of binding IDA
 biological_processGO:0051571 positive regulation of histone H3-K4 methylation IMP
 biological_processGO:0051797 regulation of hair follicle development IMP
 biological_processGO:0060065 uterus development IGI
 biological_processGO:0060391 positive regulation of SMAD protein signal transduction IMP
 biological_processGO:0060395 SMAD protein signal transduction ISO
 biological_processGO:0060412 ventricular septum morphogenesis IMP
 biological_processGO:0060548 negative regulation of cell death IMP
 biological_processGO:0060956 endocardial cell differentiation IMP
 biological_processGO:0061040 female gonad morphogenesis IMP
 biological_processGO:0061614 pri-miRNA transcription by RNA polymerase II IMP
 biological_processGO:0062009 secondary palate development IMP
 biological_processGO:0070102 interleukin-6-mediated signaling pathway IDA
 biological_processGO:0070207 protein homotrimerization ISO
 biological_processGO:0070371 ERK1 and ERK2 cascade ISO
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0071333 cellular response to glucose stimulus ISO
 biological_processGO:0071559 response to transforming growth factor beta ISO
 biological_processGO:0072133 metanephric mesenchyme morphogenesis IMP
 biological_processGO:0072134 nephrogenic mesenchyme morphogenesis IMP
 biological_processGO:0072520 seminiferous tubule development IMP
 biological_processGO:1905305 negative regulation of cardiac myofibril assembly IMP
 biological_processGO:2000617 positive regulation of histone H3-K9 acetylation IMP
 cellular_componentGO:0000790 nuclear chromatin ISO
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005667 transcription factor complex ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0032444 activin responsive factor complex ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0071141 SMAD protein complex ISO
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IGI
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0000989 transcription factor activity, transcription factor binding ISO
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IPI
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IGI
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding IPI
 molecular_functionGO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity ISO
 molecular_functionGO:0031005 filamin binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043199 sulfate binding ISO
 molecular_functionGO:0043565 sequence-specific DNA binding ISO
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISO
 molecular_functionGO:0046332 SMAD binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0070411 I-SMAD binding ISO
 molecular_functionGO:0070412 R-SMAD binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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