17685


Mus musculus (NCBI)

Features
Gene ID: 17685
  
Biological name :
  
Synonyms : AI788990 / Msh2 / mutS homolog 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1416988_at (Mouse Genome 430 2.0 Array)   1447888_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6678938
RefSeq - NC_000083.6
RefSeq - NP_032654.1
RefSeq - NM_008628.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000024151 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000710 meiotic mismatch repair IBA
 biological_processGO:0001701 in utero embryonic development IGI
 biological_processGO:0002204 somatic recombination of immunoglobulin genes involved in immune response IGI
 biological_processGO:0006119 oxidative phosphorylation IMP
 biological_processGO:0006281 DNA repair ISO
 biological_processGO:0006290 pyrimidine dimer repair IBA
 biological_processGO:0006298 mismatch repair ISO
 biological_processGO:0006301 postreplication repair ISO
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006311 meiotic gene conversion IBA
 biological_processGO:0006312 mitotic recombination IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest IMP
 biological_processGO:0007281 germ cell development IMP
 biological_processGO:0007283 spermatogenesis IBA
 biological_processGO:0008340 determination of adult lifespan IMP
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IMP
 biological_processGO:0010165 response to X-ray IMP
 biological_processGO:0010224 response to UV-B IMP
 biological_processGO:0016446 somatic hypermutation of immunoglobulin genes IMP
 biological_processGO:0016447 somatic recombination of immunoglobulin gene segments IMP
 biological_processGO:0019724 B cell mediated immunity IMP
 biological_processGO:0030183 B cell differentiation IMP
 biological_processGO:0031573 intra-S DNA damage checkpoint IGI
 biological_processGO:0036297 interstrand cross-link repair IBA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IGI
 biological_processGO:0043111 replication fork arrest IBA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0043570 maintenance of DNA repeat elements ISO
 biological_processGO:0045128 negative regulation of reciprocal meiotic recombination IBA
 biological_processGO:0045190 isotype switching IMP
 biological_processGO:0045910 negative regulation of DNA recombination ISO
 biological_processGO:0048298 positive regulation of isotype switching to IgA isotypes IMP
 biological_processGO:0048304 positive regulation of isotype switching to IgG isotypes IMP
 biological_processGO:0051096 positive regulation of helicase activity ISO
 cellular_componentGO:0000228 nuclear chromosome IBA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0032300 mismatch repair complex IEA
 cellular_componentGO:0032301 MutSalpha complex ISO
 cellular_componentGO:0032302 MutSbeta complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0000400 four-way junction DNA binding ISO
 molecular_functionGO:0000403 Y-form DNA binding IBA
 molecular_functionGO:0000404 heteroduplex DNA loop binding IBA
 molecular_functionGO:0000406 double-strand/single-strand DNA junction binding IBA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003684 damaged DNA binding IMP
 molecular_functionGO:0003690 double-stranded DNA binding ISO
 molecular_functionGO:0003697 single-stranded DNA binding ISO
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0008094 DNA-dependent ATPase activity IBA
 molecular_functionGO:0016887 ATPase activity ISO
 molecular_functionGO:0019237 centromeric DNA binding IDA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0030983 mismatched DNA binding ISO
 molecular_functionGO:0032137 guanine/thymine mispair binding ISO
 molecular_functionGO:0032138 single base insertion or deletion binding IBA
 molecular_functionGO:0032139 dinucleotide insertion or deletion binding ISO
 molecular_functionGO:0032142 single guanine insertion binding ISO
 molecular_functionGO:0032143 single thymine insertion binding ISO
 molecular_functionGO:0032181 dinucleotide repeat insertion binding ISO
 molecular_functionGO:0032357 oxidized purine DNA binding ISO
 molecular_functionGO:0032405 MutLalpha complex binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043531 ADP binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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