177


Homo sapiens (NCBI)

Features
Gene ID: 177
  
Biological name :
  
Synonyms : advanced glycosylation end-product specific receptor / AGER / RAGE|SCARJ1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210081_at (Human Genome U133 Plus 2.0 Array)   217046_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001193895.1
RefSeq - NP_751947.1
RefSeq - NC_000006.12
RefSeq - NT_113891.3
RefSeq - NT_167244.2
RefSeq - NT_167246.2
RefSeq - NT_167247.2
RefSeq - NT_167248.2
RefSeq - NT_167249.2
RefSeq - NG_029868.1
RefSeq - XP_016865817.1
RefSeq - 10835203
RefSeq - 1034648671
RefSeq - 26787962
RefSeq - 332800965
RefSeq - 332800967
RefSeq - 332800969
RefSeq - 332800971
RefSeq - 332800973
RefSeq - 332800985
RefSeq - 332800988
RefSeq - NP_001127.1
RefSeq - NP_001193858.1
RefSeq - NP_001193861.1
RefSeq - NP_001193863.1
RefSeq - NP_001193865.1
RefSeq - NP_001193869.1
RefSeq - NP_001193883.1
RefSeq - XR_001743190.2
RefSeq - NM_001136.4
RefSeq - NM_001206929.1
RefSeq - NM_001206932.1
RefSeq - NM_001206934.1
RefSeq - NM_001206936.1
RefSeq - NM_001206940.1
RefSeq - NM_001206954.1
RefSeq - NM_001206966.1
RefSeq - NM_172197.2
RefSeq - NR_038190.1
RefSeq - XM_017010328.2
RefSeq - XR_001743189.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000204305 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001914 regulation of T cell mediated cytotoxicity IDA
 biological_processGO:0001934 positive regulation of protein phosphorylation IGI
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007611 learning or memory IGI
 biological_processGO:0009611 response to wounding TAS
 biological_processGO:0010255 glucose mediated signaling pathway IDA
 biological_processGO:0014002 astrocyte development IEA
 biological_processGO:0031175 neuron projection development IGI
 biological_processGO:0032693 negative regulation of interleukin-10 production IDA
 biological_processGO:0032735 positive regulation of interleukin-12 production IMP
 biological_processGO:0042104 positive regulation of activated T cell proliferation IMP
 biological_processGO:0043507 positive regulation of JUN kinase activity IEA
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0046330 positive regulation of JNK cascade IGI
 biological_processGO:0048167 regulation of synaptic plasticity TAS
 biological_processGO:0050930 induction of positive chemotaxis IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IGI
 biological_processGO:0051101 regulation of DNA binding IEA
 biological_processGO:0061890 positive regulation of astrocyte activation IGI
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IGI
 biological_processGO:0071639 positive regulation of monocyte chemotactic protein-1 production IEA
 biological_processGO:0072657 protein localization to membrane IEA
 biological_processGO:0090647 modulation of age-related behavioral decline IGI
 biological_processGO:0150003 regulation of spontaneous synaptic transmission IGI
 biological_processGO:1900271 regulation of long-term synaptic potentiation ISS
 biological_processGO:1900272 negative regulation of long-term synaptic potentiation ISS
 biological_processGO:1900453 negative regulation of long term synaptic depression IGI
 biological_processGO:1900744 regulation of p38MAPK cascade ISS
 biological_processGO:1900745 positive regulation of p38MAPK cascade IGI
 biological_processGO:1901222 regulation of NIK/NF-kappaB signaling NAS
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IGI
 biological_processGO:1903980 positive regulation of microglial cell activation IGI
 biological_processGO:1904597 negative regulation of connective tissue replacement involved in inflammatory response wound healing IEA
 biological_processGO:1904604 negative regulation of advanced glycation end-product receptor activity IEA
 biological_processGO:1904645 response to amyloid-beta TAS
 biological_processGO:1904646 cellular response to amyloid-beta ISS
 biological_processGO:2000514 regulation of CD4-positive, alpha-beta T cell activation IDA
 biological_processGO:2001200 positive regulation of dendritic cell differentiation IMP
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0009986 cell surface NAS
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0098794 postsynapse TAS
 molecular_functionGO:0001540 amyloid-beta binding TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005044 scavenger receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0038023 signaling receptor activity IMP
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0044548 S100 protein binding IPI
 molecular_functionGO:0050785 advanced glycation end-product receptor activity NAS
 molecular_functionGO:1904599 advanced glycation end-product binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr