18024


Mus musculus (NCBI)

Features
Gene ID: 18024
  
Biological name :
  
Synonyms : Nfe2l2 / Nrf2 / nuclear factor, erythroid derived 2, like 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1416543_at (Mouse Genome 430 2.0 Array)   1457117_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6754832
RefSeq - NC_000068.7
RefSeq - NP_035032.1
RefSeq - NM_010902.4
RefSeq - NR_132727.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000015839 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006954 inflammatory response IMP
 biological_processGO:0010499 proteasomal ubiquitin-independent protein catabolic process ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process ISO
 biological_processGO:0010976 positive regulation of neuron projection development ISO
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0030194 positive regulation of blood coagulation IMP
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IDA
 biological_processGO:0034599 cellular response to oxidative stress IMP
 biological_processGO:0034976 response to endoplasmic reticulum stress IMP
 biological_processGO:0035690 cellular response to drug IMP
 biological_processGO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress ISO
 biological_processGO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress ISO
 biological_processGO:0036499 PERK-mediated unfolded protein response IDA
 biological_processGO:0042149 cellular response to glucose starvation IMP
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process ISO
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0045454 cell redox homeostasis IMP
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0045995 regulation of embryonic development IGI
 biological_processGO:0046223 aflatoxin catabolic process ISO
 biological_processGO:0046326 positive regulation of glucose import IDA
 biological_processGO:0060548 negative regulation of cell death ISO
 biological_processGO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia ISO
 biological_processGO:0070301 cellular response to hydrogen peroxide ISO
 biological_processGO:0071356 cellular response to tumor necrosis factor ISO
 biological_processGO:0071498 cellular response to fluid shear stress ISO
 biological_processGO:0071499 cellular response to laminar fluid shear stress ISO
 biological_processGO:1902037 negative regulation of hematopoietic stem cell differentiation IMP
 biological_processGO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway ISO
 biological_processGO:1903206 negative regulation of hydrogen peroxide-induced cell death ISO
 biological_processGO:1903788 positive regulation of glutathione biosynthetic process IMP
 biological_processGO:1904753 negative regulation of vascular associated smooth muscle cell migration ISO
 biological_processGO:2000121 regulation of removal of superoxide radicals IMP
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process ISO
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IMP
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0032993 protein-DNA complex IDA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding ISO
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0001221 transcription cofactor binding ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0043565 sequence-specific DNA binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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