18091


Mus musculus (NCBI)

Features
Gene ID: 18091
  
Biological name :
  
Synonyms : Csx|Nkx-2.5|Nkx2.5|tinman / NK2 homeobox 5 / Nkx2-5
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1449566_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6679068
RefSeq - XP_006523860.1
RefSeq - NC_000083.6
RefSeq - 568999306
RefSeq - NP_032726.1
RefSeq - NM_008700.2
RefSeq - XM_006523797.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000015579 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0003148 outflow tract septum morphogenesis ISO
 biological_processGO:0003151 outflow tract morphogenesis IMP
 biological_processGO:0003161 cardiac conduction system development ISO
 biological_processGO:0003162 atrioventricular node development IMP
 biological_processGO:0003166 bundle of His development IGI
 biological_processGO:0003168 Purkinje myocyte differentiation IMP
 biological_processGO:0003208 cardiac ventricle morphogenesis IMP
 biological_processGO:0003211 cardiac ventricle formation IGI
 biological_processGO:0003221 right ventricular cardiac muscle tissue morphogenesis ISO
 biological_processGO:0003222 ventricular trabecula myocardium morphogenesis IMP
 biological_processGO:0003278 apoptotic process involved in heart morphogenesis IMP
 biological_processGO:0003285 septum secundum development ISO
 biological_processGO:0003342 proepicardium development IMP
 biological_processGO:0003350 pulmonary myocardium development IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007492 endoderm development TAS
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007512 adult heart development ISO
 biological_processGO:0008284 positive regulation of cell proliferation IGI
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process ISO
 biological_processGO:0010735 positive regulation of transcription via serum response element binding IDA
 biological_processGO:0010765 positive regulation of sodium ion transport IMP
 biological_processGO:0010832 negative regulation of myotube differentiation ISO
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030154 cell differentiation IGI
 biological_processGO:0030509 BMP signaling pathway IDA
 biological_processGO:0030878 thyroid gland development ISO
 biological_processGO:0035050 embryonic heart tube development IGI
 biological_processGO:0043066 negative regulation of apoptotic process IGI
 biological_processGO:0043586 tongue development TAS
 biological_processGO:0045214 sarcomere organization IGI
 biological_processGO:0045666 positive regulation of neuron differentiation ISO
 biological_processGO:0045823 positive regulation of heart contraction IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048536 spleen development TAS
 biological_processGO:0048738 cardiac muscle tissue development IMP
 biological_processGO:0051891 positive regulation of cardioblast differentiation IMP
 biological_processGO:0055005 ventricular cardiac myofibril assembly IMP
 biological_processGO:0055007 cardiac muscle cell differentiation TAS
 biological_processGO:0055008 cardiac muscle tissue morphogenesis ISO
 biological_processGO:0055014 atrial cardiac muscle cell development TAS
 biological_processGO:0055015 ventricular cardiac muscle cell development TAS
 biological_processGO:0055117 regulation of cardiac muscle contraction IMP
 biological_processGO:0060037 pharyngeal system development IGI
 biological_processGO:0060038 cardiac muscle cell proliferation IGI
 biological_processGO:0060043 regulation of cardiac muscle cell proliferation IDA
 biological_processGO:0060047 heart contraction IGI
 biological_processGO:0060048 cardiac muscle contraction IMP
 biological_processGO:0060070 canonical Wnt signaling pathway IDA
 biological_processGO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter IDA
 biological_processGO:0060347 heart trabecula formation IMP
 biological_processGO:0060412 ventricular septum morphogenesis ISO
 biological_processGO:0060413 atrial septum morphogenesis ISO
 biological_processGO:0060928 atrioventricular node cell development IMP
 biological_processGO:0060929 atrioventricular node cell fate commitment IMP
 biological_processGO:0060971 embryonic heart tube left/right pattern formation IMP
 biological_processGO:0072358 cardiovascular system development IGI
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IDA
 biological_processGO:1903779 regulation of cardiac conduction IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005667 transcription factor complex IPI
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0032993 protein-DNA complex ISO
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding IMP
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003682 chromatin binding ISO
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IDA
 molecular_functionGO:0003712 transcription coregulator activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0010736 serum response element binding IDA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0042826 histone deacetylase binding ISO
 molecular_functionGO:0043565 sequence-specific DNA binding ISO
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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