18127


Mus musculus (NCBI)

Features
Gene ID: 18127
  
Biological name :
  
Synonyms : 2310065A03Rik|Nos-3|eNOS|ecNOS / nitric oxide synthase 3, endothelial cell / Nos3
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422622_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 568933039
RefSeq - XP_006535702.1
RefSeq - NC_000071.6
RefSeq - 161086988
RefSeq - NP_032739.3
RefSeq - NM_008713.4
RefSeq - XM_006535639.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000028978 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001542 ovulation from ovarian follicle IMP
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001974 blood vessel remodeling IMP
 biological_processGO:0002028 regulation of sodium ion transport IMP
 biological_processGO:0003057 regulation of the force of heart contraction by chemical signal IGI
 biological_processGO:0003100 regulation of systemic arterial blood pressure by endothelin ISO
 biological_processGO:0003180 aortic valve morphogenesis IMP
 biological_processGO:0003184 pulmonary valve morphogenesis IGI
 biological_processGO:0003203 endocardial cushion morphogenesis IGI
 biological_processGO:0006527 arginine catabolic process ISO
 biological_processGO:0006809 nitric oxide biosynthetic process ISO
 biological_processGO:0007165 signal transduction ISO
 biological_processGO:0007263 nitric oxide mediated signal transduction IBA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0009725 response to hormone IBA
 biological_processGO:0010628 positive regulation of gene expression IGI
 biological_processGO:0014740 negative regulation of muscle hyperplasia IMP
 biological_processGO:0014806 smooth muscle hyperplasia IMP
 biological_processGO:0019430 removal of superoxide radicals ISO
 biological_processGO:0030324 lung development IMP
 biological_processGO:0031284 positive regulation of guanylate cyclase activity ISO
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IMP
 biological_processGO:0032355 response to estradiol ISO
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043267 negative regulation of potassium ion transport IMP
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0043542 endothelial cell migration ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0045776 negative regulation of blood pressure IBA
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation ISO
 biological_processGO:0048873 homeostasis of number of cells within a tissue IGI
 biological_processGO:0050880 regulation of blood vessel size IMP
 biological_processGO:0051346 negative regulation of hydrolase activity IMP
 biological_processGO:0051926 negative regulation of calcium ion transport IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060412 ventricular septum morphogenesis IGI
 biological_processGO:0070168 negative regulation of biomineral tissue development IMP
 biological_processGO:0071260 cellular response to mechanical stimulus ISO
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus ISO
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005901 caveola ISO
 cellular_componentGO:0012506 vesicle membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042383 sarcolemma ISO
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0045177 apical part of cell ISO
 molecular_functionGO:0003779 actin binding ISO
 molecular_functionGO:0003785 actin monomer binding ISO
 molecular_functionGO:0003958 NADPH-hemoprotein reductase activity IBA
 molecular_functionGO:0004517 nitric-oxide synthase activity ISO
 molecular_functionGO:0005516 calmodulin binding ISO
 molecular_functionGO:0008013 beta-catenin binding ISO
 molecular_functionGO:0010181 FMN binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen IBA
 molecular_functionGO:0020037 heme binding ISO
 molecular_functionGO:0034617 tetrahydrobiopterin binding ISO
 molecular_functionGO:0034618 arginine binding ISO
 molecular_functionGO:0045296 cadherin binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0050661 NADP binding IEA
 molecular_functionGO:0050998 nitric-oxide synthase binding ISO
 molecular_functionGO:0051879 Hsp90 protein binding ISO
 molecular_functionGO:0097110 scaffold protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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