1813


Homo sapiens (NCBI)

Features
Gene ID: 1813
  
Biological name :
  
Synonyms : D2DR|D2R / dopamine receptor D2 / DRD2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206590_x_at (Human Genome U133 Plus 2.0 Array)   211624_s_at (Human Genome U133 Plus 2.0 Array)   216924_s_at (Human Genome U133 Plus 2.0 Array)   216938_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034572281
RefSeq - 17986270
RefSeq - 4503385
RefSeq - NC_000011.10
RefSeq - NG_008841.1
RefSeq - NP_000786.1
RefSeq - NP_057658.2
RefSeq - XP_016872785.1
RefSeq - NM_000795.3
RefSeq - NM_016574.3
RefSeq - XM_017017296.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000149295 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001659 temperature homeostasis ISS
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0001975 response to amphetamine ISS
 biological_processGO:0001976 neurological system process involved in regulation of systemic arterial blood pressure ISS
 biological_processGO:0002027 regulation of heart rate ISS
 biological_processGO:0002028 regulation of sodium ion transport ISS
 biological_processGO:0002031 G-protein coupled receptor internalization IEA
 biological_processGO:0002052 positive regulation of neuroblast proliferation ISS
 biological_processGO:0002092 positive regulation of receptor internalization IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway IDA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0007270 neuron-neuron synaptic transmission ISS
 biological_processGO:0007409 axonogenesis ISS
 biological_processGO:0007416 synapse assembly ISS
 biological_processGO:0007608 sensory perception of smell ISS
 biological_processGO:0007616 long-term memory IEA
 biological_processGO:0007625 grooming behavior IEA
 biological_processGO:0007626 locomotory behavior ISS
 biological_processGO:0007628 adult walking behavior ISS
 biological_processGO:0008104 protein localization ISS
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0008306 associative learning ISS
 biological_processGO:0008542 visual learning ISS
 biological_processGO:0009416 response to light stimulus ISS
 biological_processGO:0010039 response to iron ion IEA
 biological_processGO:0014854 response to inactivity IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0021756 striatum development IEA
 biological_processGO:0021769 orbitofrontal cortex development IEA
 biological_processGO:0021853 cerebral cortex GABAergic interneuron migration ISS
 biological_processGO:0021984 adenohypophysis development ISS
 biological_processGO:0030336 negative regulation of cell migration ISS
 biological_processGO:0030432 peristalsis ISS
 biological_processGO:0031223 auditory behavior IEA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0032228 regulation of synaptic transmission, GABAergic ISS
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0032922 circadian regulation of gene expression ISS
 biological_processGO:0033602 negative regulation of dopamine secretion IEA
 biological_processGO:0034776 response to histamine IDA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0035810 positive regulation of urine volume IEA
 biological_processGO:0035815 positive regulation of renal sodium excretion IEA
 biological_processGO:0040018 positive regulation of multicellular organism growth IEA
 biological_processGO:0042220 response to cocaine ISS
 biological_processGO:0042321 negative regulation of circadian sleep/wake cycle, sleep IEA
 biological_processGO:0042417 dopamine metabolic process IC
 biological_processGO:0042493 response to drug ISS
 biological_processGO:0042756 drinking behavior IEA
 biological_processGO:0043266 regulation of potassium ion transport ISS
 biological_processGO:0043278 response to morphine ISS
 biological_processGO:0043473 pigmentation IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0045776 negative regulation of blood pressure ISS
 biological_processGO:0045824 negative regulation of innate immune response IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046676 negative regulation of insulin secretion IEA
 biological_processGO:0048148 behavioral response to cocaine ISS
 biological_processGO:0048149 behavioral response to ethanol ISS
 biological_processGO:0048169 regulation of long-term neuronal synaptic plasticity ISS
 biological_processGO:0048678 response to axon injury IEA
 biological_processGO:0048755 branching morphogenesis of a nerve ISS
 biological_processGO:0050482 arachidonic acid secretion IDA
 biological_processGO:0050709 negative regulation of protein secretion IDA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol ISS
 biological_processGO:0051584 regulation of dopamine uptake involved in synaptic transmission IC
 biological_processGO:0051586 positive regulation of dopamine uptake involved in synaptic transmission ISS
 biological_processGO:0051823 regulation of synapse structural plasticity IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling NAS
 biological_processGO:0051967 negative regulation of synaptic transmission, glutamatergic ISS
 biological_processGO:0060079 excitatory postsynaptic potential NAS
 biological_processGO:0060124 positive regulation of growth hormone secretion ISS
 biological_processGO:0060134 prepulse inhibition ISS
 biological_processGO:0060158 phospholipase C-activating dopamine receptor signaling pathway IGI
 biological_processGO:0060160 negative regulation of dopamine receptor signaling pathway ISS
 biological_processGO:0060548 negative regulation of cell death IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway IBA
 biological_processGO:0090325 regulation of locomotion involved in locomotory behavior IEA
 biological_processGO:1900168 positive regulation of glial cell-derived neurotrophic factor secretion IDA
 biological_processGO:1900273 positive regulation of long-term synaptic potentiation IEA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016328 lateral plasma membrane IEA
 cellular_componentGO:0030139 endocytic vesicle IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0036126 sperm flagellum IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0043679 axon terminus IEA
 cellular_componentGO:0060170 ciliary membrane IDA
 cellular_componentGO:0097730 non-motile cilium IDA
 molecular_functionGO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go IDA
 molecular_functionGO:0004935 adrenergic receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding IDA
 molecular_functionGO:0035255 ionotropic glutamate receptor binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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