1815


Homo sapiens (NCBI)

Features
Gene ID: 1815
  
Biological name :
  
Synonyms : D4DR / dopamine receptor D4 / DRD4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208215_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 32483397
RefSeq - NC_000011.10
RefSeq - NG_021241.1
RefSeq - NP_000788.2
RefSeq - NT_187586.1
RefSeq - NM_000797.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000069696 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IDA
 biological_processGO:0001662 behavioral fear response NAS
 biological_processGO:0001975 response to amphetamine ISS
 biological_processGO:0006874 cellular calcium ion homeostasis IC
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IBA
 biological_processGO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway IMP
 biological_processGO:0007212 dopamine receptor signaling pathway IDA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0008344 adult locomotory behavior ISS
 biological_processGO:0032417 positive regulation of sodium:proton antiporter activity IDA
 biological_processGO:0033674 positive regulation of kinase activity IDA
 biological_processGO:0034776 response to histamine IDA
 biological_processGO:0035176 social behavior NAS
 biological_processGO:0042053 regulation of dopamine metabolic process ISS
 biological_processGO:0042417 dopamine metabolic process IC
 biological_processGO:0042596 fear response ISS
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0048148 behavioral response to cocaine ISS
 biological_processGO:0048149 behavioral response to ethanol TAS
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0050482 arachidonic acid secretion IDA
 biological_processGO:0050709 negative regulation of protein secretion IDA
 biological_processGO:0051586 positive regulation of dopamine uptake involved in synaptic transmission IC
 biological_processGO:0060080 inhibitory postsynaptic potential ISS
 biological_processGO:1901386 negative regulation of voltage-gated calcium channel activity IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030425 dendrite IBA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go ISS
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA
 molecular_functionGO:0004952 dopamine neurotransmitter receptor activity IDA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding IDA
 molecular_functionGO:0015459 potassium channel regulator activity NAS
 molecular_functionGO:0017124 SH3 domain binding IDA
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA
 molecular_functionGO:0035240 dopamine binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051379 epinephrine binding IDA
 molecular_functionGO:0051380 norepinephrine binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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