18211


Mus musculus (NCBI)

Features
Gene ID: 18211
  
Biological name :
  
Synonyms : C80751|Tkr|TrkA|trk / neurotrophic tyrosine kinase, receptor, type 1 / Ntrk1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1443990_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 568922049
RefSeq - XP_006501187.1
RefSeq - NC_000069.6
RefSeq - 169234626
RefSeq - NP_001028296.1
RefSeq - NM_001033124.1
RefSeq - XM_006501124.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000028072 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IDA
 biological_processGO:0007411 axon guidance ISO
 biological_processGO:0007611 learning or memory ISO
 biological_processGO:0007623 circadian rhythm IEP
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010623 programmed cell death involved in cell development ISO
 biological_processGO:0010976 positive regulation of neuron projection development ISO
 biological_processGO:0014823 response to activity ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0019233 sensory perception of pain ISO
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030183 B cell differentiation IMP
 biological_processGO:0031175 neuron projection development ISO
 biological_processGO:0031667 response to nutrient levels ISO
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035094 response to nicotine ISO
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation ISO
 biological_processGO:0038180 nerve growth factor signaling pathway ISO
 biological_processGO:0042490 mechanoreceptor differentiation IMP
 biological_processGO:0042493 response to drug ISO
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043068 positive regulation of programmed cell death ISO
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0043547 positive regulation of GTPase activity ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0046579 positive regulation of Ras protein signal transduction ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway ISO
 biological_processGO:0048485 sympathetic nervous system development IMP
 biological_processGO:0048666 neuron development ISO
 biological_processGO:0050965 detection of temperature stimulus involved in sensory perception of pain ISO
 biological_processGO:0050966 detection of mechanical stimulus involved in sensory perception of pain ISO
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0051602 response to electrical stimulus ISO
 biological_processGO:0051965 positive regulation of synapse assembly IDA
 biological_processGO:0051968 positive regulation of synaptic transmission, glutamatergic ISO
 biological_processGO:0060009 Sertoli cell development ISO
 biological_processGO:0060384 innervation IMP
 biological_processGO:0060385 axonogenesis involved in innervation IMP
 biological_processGO:0061368 behavioral response to formalin induced pain IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071316 cellular response to nicotine ISO
 biological_processGO:0071363 cellular response to growth factor stimulus ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:1990090 cellular response to nerve growth factor stimulus ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005770 late endosome ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043235 receptor complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity ISO
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005004 GPI-linked ephrin receptor activity ISO
 molecular_functionGO:0005030 neurotrophin receptor activity IEA
 molecular_functionGO:0005166 neurotrophin p75 receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0010465 nerve growth factor receptor activity ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019900 kinase binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043121 neurotrophin binding IBA
 molecular_functionGO:0048406 nerve growth factor binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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