18212


Mus musculus (NCBI)

Features
Gene ID: 18212
  
Biological name :
  
Synonyms : GP145-TrkB/GP95-TrkB|Tkrb|trk-B|trkB / neurotrophic tyrosine kinase, receptor, type 2 / Ntrk2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1420837_at (Mouse Genome 430 2.0 Array)   1420838_at (Mouse Genome 430 2.0 Array)   1435196_at (Mouse Genome 430 2.0 Array)   1435305_at (Mouse Genome 430 2.0 Array)   1437560_at (Mouse Genome 430 2.0 Array)   1444121_at (Mouse Genome 430 2.0 Array)   1446712_at (Mouse Genome 430 2.0 Array)   1458622_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_017170909.1
RefSeq - 1039743300
RefSeq - 545478683
RefSeq - 568983144
RefSeq - 568983146
RefSeq - 568983148
RefSeq - 568983150
RefSeq - 6679150
RefSeq - 68215970
RefSeq - NC_000079.6
RefSeq - NP_001020245.1
RefSeq - NP_001269890.1
RefSeq - NP_032771.1
RefSeq - XP_006517212.1
RefSeq - XP_006517213.1
RefSeq - XP_006517214.1
RefSeq - XP_006517215.1
RefSeq - XP_017170908.1
RefSeq - 1039743295
RefSeq - NM_001025074.2
RefSeq - NM_001282961.1
RefSeq - NM_008745.3
RefSeq - XM_006517152.3
RefSeq - XM_017315419.1
RefSeq - XM_017315420.1
RefSeq - XM_006517149.3
RefSeq - XM_006517150.3
RefSeq - XM_006517151.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000055254 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007528 neuromuscular junction development IMP
 biological_processGO:0007612 learning IMP
 biological_processGO:0007616 long-term memory ISO
 biological_processGO:0007623 circadian rhythm IEP
 biological_processGO:0007631 feeding behavior IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010976 positive regulation of neuron projection development IDA
 biological_processGO:0014047 glutamate secretion IPI
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0019222 regulation of metabolic process IMP
 biological_processGO:0021954 central nervous system neuron development IMP
 biological_processGO:0021987 cerebral cortex development IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0031547 brain-derived neurotrophic factor receptor signaling pathway ISO
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IMP
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source IMP
 biological_processGO:0042490 mechanoreceptor differentiation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043087 regulation of GTPase activity IDA
 biological_processGO:0043408 regulation of MAPK cascade ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0046548 retinal rod cell development IMP
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0046928 regulation of neurotransmitter secretion ISO
 biological_processGO:0048709 oligodendrocyte differentiation IMP
 biological_processGO:0048935 peripheral nervous system neuron development IMP
 biological_processGO:0050772 positive regulation of axonogenesis ISO
 biological_processGO:0050773 regulation of dendrite development ISO
 biological_processGO:0051896 regulation of protein kinase B signaling IMP
 biological_processGO:0051965 positive regulation of synapse assembly IDA
 biological_processGO:0051968 positive regulation of synaptic transmission, glutamatergic ISO
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0060291 long-term synaptic potentiation IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071230 cellular response to amino acid stimulus IDA
 biological_processGO:0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission IMP
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IBA
 biological_processGO:2000324 positive regulation of glucocorticoid receptor signaling pathway ISO
 biological_processGO:2000811 negative regulation of anoikis IDA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005791 rough endoplasmic reticulum ISO
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0014069 postsynaptic density ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0030426 growth cone ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043195 terminal bouton IDA
 cellular_componentGO:0043197 dendritic spine ISO
 cellular_componentGO:0043204 perikaryon ISO
 cellular_componentGO:0043235 receptor complex ISO
 cellular_componentGO:0043679 axon terminus ISO
 cellular_componentGO:0045211 postsynaptic membrane IDA
 cellular_componentGO:0048786 presynaptic active zone ISO
 cellular_componentGO:0060076 excitatory synapse ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity ISO
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005030 neurotrophin receptor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043121 neurotrophin binding ISO
 molecular_functionGO:0048403 brain-derived neurotrophic factor binding ISO
 molecular_functionGO:0060175 brain-derived neurotrophic factor-activated receptor activity ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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