18439


Mus musculus (NCBI)

Features
Gene ID: 18439
  
Biological name :
  
Synonyms : AI467586|P2X(7)|P2X7R / P2rx7 / purinergic receptor P2X, ligand-gated ion channel, 7
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1419853_a_at (Mouse Genome 430 2.0 Array)   1422218_at (Mouse Genome 430 2.0 Array)   1439787_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 548923886
RefSeq - 84781760
RefSeq - 84781762
RefSeq - 84781764
RefSeq - 84781766
RefSeq - NC_000071.6
RefSeq - NP_001033928.1
RefSeq - NP_001033934.1
RefSeq - NP_001033976.1
RefSeq - NP_001271331.1
RefSeq - NP_035157.2
RefSeq - NM_001038839.2
RefSeq - NM_001038845.2
RefSeq - NM_001038887.1
RefSeq - NM_001284402.1
RefSeq - NM_011027.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000029468 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IMP
 biological_processGO:0000902 cell morphogenesis IMP
 biological_processGO:0001845 phagolysosome assembly IMP
 biological_processGO:0001916 positive regulation of T cell mediated cytotoxicity IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0006468 protein phosphorylation IMP
 biological_processGO:0006509 membrane protein ectodomain proteolysis IMP
 biological_processGO:0006649 phospholipid transfer to membrane IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IMP
 biological_processGO:0006816 calcium ion transport IMP
 biological_processGO:0006884 cell volume homeostasis IDA
 biological_processGO:0006900 vesicle budding from membrane IMP
 biological_processGO:0006954 inflammatory response IMP
 biological_processGO:0007005 mitochondrion organization IDA
 biological_processGO:0007009 plasma membrane organization IDA
 biological_processGO:0009612 response to mechanical stimulus IMP
 biological_processGO:0009617 response to bacterium IMP
 biological_processGO:0010033 response to organic substance IMP
 biological_processGO:0010043 response to zinc ion IMP
 biological_processGO:0010467 gene expression IMP
 biological_processGO:0010524 positive regulation of calcium ion transport into cytosol ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0012501 programmed cell death IMP
 biological_processGO:0014049 positive regulation of glutamate secretion IMP
 biological_processGO:0014054 positive regulation of gamma-aminobutyric acid secretion IMP
 biological_processGO:0014070 response to organic cyclic compound IDA
 biological_processGO:0016079 synaptic vesicle exocytosis IMP
 biological_processGO:0016485 protein processing IMP
 biological_processGO:0017121 phospholipid scrambling ISO
 biological_processGO:0019233 sensory perception of pain IMP
 biological_processGO:0019835 cytolysis IMP
 biological_processGO:0030163 protein catabolic process IDA
 biological_processGO:0030501 positive regulation of bone mineralization IMP
 biological_processGO:0031668 cellular response to extracellular stimulus IMP
 biological_processGO:0032060 bleb assembly ISO
 biological_processGO:0032308 positive regulation of prostaglandin secretion IMP
 biological_processGO:0032496 response to lipopolysaccharide IMP
 biological_processGO:0032731 positive regulation of interleukin-1 beta production IMP
 biological_processGO:0032755 positive regulation of interleukin-6 production IMP
 biological_processGO:0032963 collagen metabolic process IMP
 biological_processGO:0033198 response to ATP ISO
 biological_processGO:0034220 ion transmembrane transport IBA
 biological_processGO:0034405 response to fluid shear stress IMP
 biological_processGO:0034767 positive regulation of ion transmembrane transport ISO
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway ISO
 biological_processGO:0042098 T cell proliferation IMP
 biological_processGO:0042493 response to drug IMP
 biological_processGO:0043029 T cell homeostasis IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0043085 positive regulation of catalytic activity IMP
 biological_processGO:0043132 NAD transport IMP
 biological_processGO:0043409 negative regulation of MAPK cascade IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0045332 phospholipid translocation IDA
 biological_processGO:0045778 positive regulation of ossification IMP
 biological_processGO:0045779 negative regulation of bone resorption IMP
 biological_processGO:0045794 negative regulation of cell volume ISO
 biological_processGO:0045821 positive regulation of glycolytic process ISO
 biological_processGO:0046513 ceramide biosynthetic process IDA
 biological_processGO:0046931 pore complex assembly ISO
 biological_processGO:0048705 skeletal system morphogenesis IMP
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 biological_processGO:0050714 positive regulation of protein secretion IDA
 biological_processGO:0050715 positive regulation of cytokine secretion IMP
 biological_processGO:0050717 positive regulation of interleukin-1 alpha secretion IMP
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion ISO
 biological_processGO:0050830 defense response to Gram-positive bacterium IMP
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IMP
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:0051592 response to calcium ion IMP
 biological_processGO:0051602 response to electrical stimulus IMP
 biological_processGO:0051899 membrane depolarization ISO
 biological_processGO:0051901 positive regulation of mitochondrial depolarization IMP
 biological_processGO:0070230 positive regulation of lymphocyte apoptotic process IMP
 biological_processGO:0071359 cellular response to dsRNA IMP
 biological_processGO:0071407 cellular response to organic cyclic compound IDA
 biological_processGO:0072593 reactive oxygen species metabolic process IMP
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IMP
 biological_processGO:0098655 cation transmembrane transport IEA
 biological_processGO:1904172 positive regulation of bleb assembly ISO
 cellular_componentGO:0005639 integral component of nuclear inner membrane IBA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031594 neuromuscular junction IDA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0045202 synapse IDA
 molecular_functionGO:0001530 lipopolysaccharide binding IDA
 molecular_functionGO:0001614 purinergic nucleotide receptor activity ISO
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity ISO
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IMP
 molecular_functionGO:0015267 channel activity ISO
 molecular_functionGO:0035381 ATP-gated ion channel activity IBA
 molecular_functionGO:0038023 signaling receptor activity IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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