18591


Mus musculus (NCBI)

Features
Gene ID: 18591
  
Biological name :
  
Synonyms : Pdgfb / PDGF-B|Sis / platelet derived growth factor, B polypeptide
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1450413_at (Mouse Genome 430 2.0 Array)   1450414_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_017171991.1
RefSeq - 40538817
RefSeq - 568991673
RefSeq - NC_000081.6
RefSeq - NP_035187.2
RefSeq - XP_006520655.1
RefSeq - 1039748437
RefSeq - NM_011057.3
RefSeq - XM_017316502.1
RefSeq - XM_006520592.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000000489 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IEP
 biological_processGO:0001892 embryonic placenta development IMP
 biological_processGO:0001938 positive regulation of endothelial cell proliferation ISO
 biological_processGO:0002548 monocyte chemotaxis ISO
 biological_processGO:0003104 positive regulation of glomerular filtration IMP
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006929 substrate-dependent cell migration IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007416 synapse assembly IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0009611 response to wounding ISO
 biological_processGO:0010512 negative regulation of phosphatidylinositol biosynthetic process ISO
 biological_processGO:0010544 negative regulation of platelet activation ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0014911 positive regulation of smooth muscle cell migration ISO
 biological_processGO:0016322 neuron remodeling IMP
 biological_processGO:0018105 peptidyl-serine phosphorylation ISO
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0021782 glial cell development IMP
 biological_processGO:0030031 cell projection assembly IDA
 biological_processGO:0030036 actin cytoskeleton organization IGI
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030336 negative regulation of cell migration IGI
 biological_processGO:0031954 positive regulation of protein autophosphorylation ISO
 biological_processGO:0032091 negative regulation of protein binding ISO
 biological_processGO:0032147 activation of protein kinase activity ISO
 biological_processGO:0032148 activation of protein kinase B activity ISO
 biological_processGO:0032967 positive regulation of collagen biosynthetic process ISO
 biological_processGO:0035655 interleukin-18-mediated signaling pathway ISO
 biological_processGO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway ISO
 biological_processGO:0038001 paracrine signaling IMP
 biological_processGO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0042462 eye photoreceptor cell development IMP
 biological_processGO:0043406 positive regulation of MAP kinase activity ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity ISO
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity ISO
 biological_processGO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway IDA
 biological_processGO:0045840 positive regulation of mitotic nuclear division ISO
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045907 positive regulation of vasoconstriction TAS
 biological_processGO:0045977 positive regulation of mitotic cell cycle, embryonic IGI
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway ISO
 biological_processGO:0048146 positive regulation of fibroblast proliferation ISO
 biological_processGO:0048514 blood vessel morphogenesis IGI
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0050921 positive regulation of chemotaxis ISO
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0060326 cell chemotaxis ISO
 biological_processGO:0060445 branching involved in salivary gland morphogenesis IMP
 biological_processGO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis IMP
 biological_processGO:0060947 cardiac vascular smooth muscle cell differentiation TAS
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity ISO
 biological_processGO:0061298 retina vasculature development in camera-type eye IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070528 protein kinase C signaling ISO
 biological_processGO:0071363 cellular response to growth factor stimulus ISO
 biological_processGO:0071506 cellular response to mycophenolic acid ISO
 biological_processGO:0072126 positive regulation of glomerular mesangial cell proliferation ISO
 biological_processGO:0072255 metanephric glomerular mesangial cell development IMP
 biological_processGO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development IMP
 biological_processGO:0072264 metanephric glomerular endothelium development IEP
 biological_processGO:0072593 reactive oxygen species metabolic process ISO
 biological_processGO:0090280 positive regulation of calcium ion import ISO
 biological_processGO:0097756 negative regulation of blood vessel diameter TAS
 biological_processGO:1900127 positive regulation of hyaluronan biosynthetic process ISO
 biological_processGO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II ISO
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II ISO
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation ISO
 biological_processGO:1904754 positive regulation of vascular associated smooth muscle cell migration ISO
 biological_processGO:1904899 positive regulation of hepatic stellate cell proliferation ISO
 biological_processGO:1905064 negative regulation of vascular smooth muscle cell differentiation ISO
 biological_processGO:1905176 positive regulation of vascular smooth muscle cell dedifferentiation ISO
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process ISO
 biological_processGO:2000491 positive regulation of hepatic stellate cell activation ISO
 biological_processGO:2000573 positive regulation of DNA biosynthetic process ISO
 biological_processGO:2000591 positive regulation of metanephric mesenchymal cell migration ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding ISO
 molecular_functionGO:0005518 collagen binding ISO
 molecular_functionGO:0008083 growth factor activity ISO
 molecular_functionGO:0016176 superoxide-generating NADPH oxidase activator activity ISO
 molecular_functionGO:0042056 chemoattractant activity ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0048407 platelet-derived growth factor binding ISO
 molecular_functionGO:0070851 growth factor receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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