18596


Mus musculus (NCBI)

Features
Gene ID: 18596
  
Biological name :
  
Synonyms : AI528809|CD140b|PDGFR-1|Pdgfr / Pdgfrb / platelet derived growth factor receptor, beta polypeptide
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1417148_at (Mouse Genome 430 2.0 Array)   1436970_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 226342982
RefSeq - 226371752
RefSeq - 755560603
RefSeq - NC_000084.6
RefSeq - NP_001139740.1
RefSeq - NP_032835.2
RefSeq - XP_011245158.1
RefSeq - NM_001146268.1
RefSeq - NM_008809.2
RefSeq - XM_011246856.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000024620 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IEP
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0001894 tissue homeostasis IMP
 biological_processGO:0006024 glycosaminoglycan biosynthetic process ISO
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006807 nitrogen compound metabolic process IMP
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0007165 signal transduction ISO
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010863 positive regulation of phospholipase C activity ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0014911 positive regulation of smooth muscle cell migration ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration ISO
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030325 adrenal gland development IGI
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0032516 positive regulation of phosphoprotein phosphatase activity ISO
 biological_processGO:0032956 regulation of actin cytoskeleton organization IGI
 biological_processGO:0032967 positive regulation of collagen biosynthetic process ISO
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction ISO
 biological_processGO:0035441 cell migration involved in vasculogenesis IMP
 biological_processGO:0035556 intracellular signal transduction ISO
 biological_processGO:0035789 metanephric mesenchymal cell migration ISO
 biological_processGO:0035791 platelet-derived growth factor receptor-beta signaling pathway ISO
 biological_processGO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway IMP
 biological_processGO:0035909 aorta morphogenesis IGI
 biological_processGO:0038091 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway ISO
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity ISO
 biological_processGO:0045840 positive regulation of mitotic nuclear division IDA
 biological_processGO:0046488 phosphatidylinositol metabolic process ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway ISO
 biological_processGO:0048015 phosphatidylinositol-mediated signaling ISO
 biological_processGO:0048146 positive regulation of fibroblast proliferation ISO
 biological_processGO:0048568 embryonic organ development IEP
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0048705 skeletal system morphogenesis IMP
 biological_processGO:0048745 smooth muscle tissue development IMP
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation IMP
 biological_processGO:0050921 positive regulation of chemotaxis IDA
 biological_processGO:0055003 cardiac myofibril assembly IGI
 biological_processGO:0060326 cell chemotaxis ISO
 biological_processGO:0060437 lung growth ISO
 biological_processGO:0060947 cardiac vascular smooth muscle cell differentiation TAS
 biological_processGO:0060981 cell migration involved in coronary angiogenesis IMP
 biological_processGO:0061298 retina vasculature development in camera-type eye IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071670 smooth muscle cell chemotaxis IGI
 biological_processGO:0072223 metanephric glomerular mesangium development IEP
 biological_processGO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development IMP
 biological_processGO:0072277 metanephric glomerular capillary formation IGI
 biological_processGO:0090280 positive regulation of calcium ion import IMP
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IMP
 biological_processGO:2000491 positive regulation of hepatic stellate cell activation ISO
 biological_processGO:2000573 positive regulation of DNA biosynthetic process IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISO
 cellular_componentGO:0031226 intrinsic component of plasma membrane ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005017 platelet-derived growth factor-activated receptor activity ISO
 molecular_functionGO:0005019 platelet-derived growth factor beta-receptor activity ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IMP
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038085 vascular endothelial growth factor binding ISO
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding ISO
 molecular_functionGO:0048407 platelet-derived growth factor binding TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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