18607


Mus musculus (NCBI)

Features
Gene ID: 18607
  
Biological name :
  
Synonyms : 3-phosphoinositide dependent protein kinase 1 / Pdk1 / Pdpk1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1415729_at (Mouse Genome 430 2.0 Array)   1416501_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_017172816.1
RefSeq - 1039752928
RefSeq - 1039752930
RefSeq - 1039752932
RefSeq - 1039752934
RefSeq - 1039752936
RefSeq - 1039752938
RefSeq - 1039752940
RefSeq - 124107594
RefSeq - 124107598
RefSeq - 557786185
RefSeq - NC_000083.6
RefSeq - NP_001074242.1
RefSeq - NP_001273591.1
RefSeq - NP_035192.2
RefSeq - XP_017172809.1
RefSeq - XP_017172810.1
RefSeq - XP_017172811.1
RefSeq - XP_017172812.1
RefSeq - XP_017172813.1
RefSeq - XP_017172814.1
RefSeq - XP_017172815.1
RefSeq - 1039752926
RefSeq - NM_001080773.2
RefSeq - NM_001286662.1
RefSeq - NM_011062.4
RefSeq - XM_017317325.1
RefSeq - XM_017317326.1
RefSeq - XM_017317327.1
RefSeq - XM_017317320.1
RefSeq - XM_017317321.1
RefSeq - XM_017317322.1
RefSeq - XM_017317323.1
RefSeq - XM_017317324.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000024122 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003323 type B pancreatic cell development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006469 negative regulation of protein kinase activity ISO
 biological_processGO:0006972 hyperosmotic response IDA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway ISO
 biological_processGO:0010518 positive regulation of phospholipase activity ISO
 biological_processGO:0010594 regulation of endothelial cell migration IMP
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration ISO
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation ISO
 biological_processGO:0019722 calcium-mediated signaling ISO
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0032148 activation of protein kinase B activity ISO
 biological_processGO:0032869 cellular response to insulin stimulus ISO
 biological_processGO:0034122 negative regulation of toll-like receptor signaling pathway IMP
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0043304 regulation of mast cell degranulation IMP
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0048041 focal adhesion assembly ISO
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol ISO
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus ISO
 biological_processGO:0097191 extrinsic apoptotic signaling pathway ISO
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane ISO
 biological_processGO:1903672 positive regulation of sprouting angiogenesis ISO
 biological_processGO:1905564 positive regulation of vascular endothelial cell proliferation ISO
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0014069 postsynaptic density IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0042995 cell projection ISO
 cellular_componentGO:0043204 perikaryon ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0004676 3-phosphoinositide-dependent protein kinase activity ISO
 molecular_functionGO:0005158 insulin receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016004 phospholipase activator activity ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0043274 phospholipase binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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