1869


Homo sapiens (NCBI)

Features
Gene ID: 1869
  
Biological name :
  
Synonyms : E2F1 / E2F-1|RBAP1|RBBP3|RBP3 / E2F transcription factor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 2028_s_at (Human Genome U133 Plus 2.0 Array)   204947_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 12669911
RefSeq - NC_000020.11
RefSeq - NG_046988.1
RefSeq - NP_005216.1
RefSeq - NM_005225.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000101412 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IMP
 biological_processGO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle TAS
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006351 transcription, DNA-templated ISS
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IMP
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0043276 anoikis IEA
 biological_processGO:0043392 negative regulation of DNA binding IDA
 biological_processGO:0045599 negative regulation of fat cell differentiation ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048146 positive regulation of fibroblast proliferation IMP
 biological_processGO:0048255 mRNA stabilization IDA
 biological_processGO:0070317 negative regulation of G0 to G1 transition TAS
 biological_processGO:0070345 negative regulation of fat cell proliferation ISS
 biological_processGO:0071398 cellular response to fatty acid IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0071466 cellular response to xenobiotic stimulus IEA
 biological_processGO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle IMP
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IEA
 biological_processGO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway TAS
 biological_processGO:1990086 lens fiber cell apoptotic process IEA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 biological_processGO:2000045 regulation of G1/S transition of mitotic cell cycle IMP
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0035189 Rb-E2F complex IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding IMP
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding ISS
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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