18708


Mus musculus (NCBI)

Features
Gene ID: 18708
  
Biological name :
  
Synonyms : phosphoinositide-3-kinase regulatory subunit 1 / PI3K|p50alpha|p55alpha|p85alpha / Pik3r1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1425514_at (Mouse Genome 430 2.0 Array)   1425515_at (Mouse Genome 430 2.0 Array)   1438682_at (Mouse Genome 430 2.0 Array)   1451737_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 117320524
RefSeq - 568984300
RefSeq - 568984302
RefSeq - 68299809
RefSeq - NC_000079.6
RefSeq - NP_001020126.1
RefSeq - NP_001070963.1
RefSeq - XP_006517632.1
RefSeq - XP_006517633.1
RefSeq - NM_001024955.2
RefSeq - NM_001077495.2
RefSeq - XM_006517569.3
RefSeq - XM_006517570.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000041417 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001678 cellular glucose homeostasis IDA
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0001953 negative regulation of cell-matrix adhesion IGI
 biological_processGO:0006006 glucose metabolic process ISO
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006606 protein import into nucleus IMP
 biological_processGO:0007162 negative regulation of cell adhesion IDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008286 insulin receptor signaling pathway ISO
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IMP
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IMP
 biological_processGO:0010459 negative regulation of heart rate ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010656 negative regulation of muscle cell apoptotic process ISO
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0022408 negative regulation of cell-cell adhesion ISO
 biological_processGO:0030183 B cell differentiation IMP
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IMP
 biological_processGO:0032868 response to insulin ISO
 biological_processGO:0032869 cellular response to insulin stimulus IDA
 biological_processGO:0033120 positive regulation of RNA splicing ISO
 biological_processGO:0034644 cellular response to UV IMP
 biological_processGO:0034976 response to endoplasmic reticulum stress ISO
 biological_processGO:0042307 positive regulation of protein import into nucleus ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043551 regulation of phosphatidylinositol 3-kinase activity ISO
 biological_processGO:0045663 positive regulation of myoblast differentiation ISO
 biological_processGO:0045671 negative regulation of osteoclast differentiation IGI
 biological_processGO:0045776 negative regulation of blood pressure ISO
 biological_processGO:0045861 negative regulation of proteolysis ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046626 regulation of insulin receptor signaling pathway IGI
 biological_processGO:0046854 phosphatidylinositol phosphorylation IBA
 biological_processGO:0048009 insulin-like growth factor receptor signaling pathway ISO
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050821 protein stabilization ISO
 biological_processGO:0051384 response to glucocorticoid ISO
 biological_processGO:0051492 regulation of stress fiber assembly IMP
 biological_processGO:0051591 response to cAMP ISO
 biological_processGO:0060396 growth hormone receptor signaling pathway ISO
 biological_processGO:1900103 positive regulation of endoplasmic reticulum unfolded protein response ISO
 biological_processGO:1903076 regulation of protein localization to plasma membrane IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005801 cis-Golgi network IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005942 phosphatidylinositol 3-kinase complex TAS
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:1990578 perinuclear endoplasmic reticulum membrane IDA
 molecular_functionGO:0001784 phosphotyrosine residue binding ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005158 insulin receptor binding ISO
 molecular_functionGO:0005159 insulin-like growth factor receptor binding ISO
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding ISO
 molecular_functionGO:0005168 neurotrophin TRKA receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding ISO
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019903 protein phosphatase binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0030331 estrogen receptor binding ISO
 molecular_functionGO:0030971 receptor tyrosine kinase binding ISO
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0035014 phosphatidylinositol 3-kinase regulator activity IEA
 molecular_functionGO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding IPI
 molecular_functionGO:0043125 ErbB-3 class receptor binding ISO
 molecular_functionGO:0043559 insulin binding ISO
 molecular_functionGO:0043560 insulin receptor substrate binding ISO
 molecular_functionGO:0046935 1-phosphatidylinositol-3-kinase regulator activity ISO
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0051117 ATPase binding ISO
 molecular_functionGO:0051219 phosphoprotein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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