18750


Mus musculus (NCBI)

Features
Gene ID: 18750
  
Biological name :
  
Synonyms : AI875142|Pkca / Prkca / protein kinase C, alpha
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1427562_a_at (Mouse Genome 430 2.0 Array)   1437393_at (Mouse Genome 430 2.0 Array)   1450945_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 164663791
RefSeq - NC_000077.6
RefSeq - NP_035231.2
RefSeq - NM_011101.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000050965 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IMP
 biological_processGO:0000302 response to reactive oxygen species ISO
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0001938 positive regulation of endothelial cell proliferation ISO
 biological_processGO:0002026 regulation of the force of heart contraction IMP
 biological_processGO:0002062 chondrocyte differentiation IDA
 biological_processGO:0002159 desmosome assembly ISO
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006469 negative regulation of protein kinase activity IMP
 biological_processGO:0006874 cellular calcium ion homeostasis IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006937 regulation of muscle contraction IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007611 learning or memory ISO
 biological_processGO:0008285 negative regulation of cell proliferation IGI
 biological_processGO:0010360 negative regulation of anion channel activity IMP
 biological_processGO:0010595 positive regulation of endothelial cell migration ISO
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0017148 negative regulation of translation ISO
 biological_processGO:0018105 peptidyl-serine phosphorylation ISO
 biological_processGO:0018107 peptidyl-threonine phosphorylation ISO
 biological_processGO:0021955 central nervous system neuron axonogenesis ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030593 neutrophil chemotaxis IMP
 biological_processGO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway ISO
 biological_processGO:0032355 response to estradiol ISO
 biological_processGO:0034351 negative regulation of glial cell apoptotic process ISO
 biological_processGO:0035408 histone H3-T6 phosphorylation ISO
 biological_processGO:0035556 intracellular signal transduction ISO
 biological_processGO:0036289 peptidyl-serine autophosphorylation IDA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0045471 response to ethanol ISO
 biological_processGO:0045651 positive regulation of macrophage differentiation IMP
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0045780 positive regulation of bone resorption IMP
 biological_processGO:0045785 positive regulation of cell adhesion ISO
 biological_processGO:0045822 negative regulation of heart contraction ISO
 biological_processGO:0045921 positive regulation of exocytosis ISO
 biological_processGO:0045931 positive regulation of mitotic cell cycle ISO
 biological_processGO:0046325 negative regulation of glucose import IMP
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IMP
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0047484 regulation of response to osmotic stress IMP
 biological_processGO:0048259 regulation of receptor-mediated endocytosis ISO
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050729 positive regulation of inflammatory response IMP
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation IMP
 biological_processGO:0050930 induction of positive chemotaxis IMP
 biological_processGO:0051965 positive regulation of synapse assembly ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070555 response to interleukin-1 ISO
 biological_processGO:0071322 cellular response to carbohydrate stimulus IDA
 biological_processGO:0090330 regulation of platelet aggregation ISO
 biological_processGO:0097193 intrinsic apoptotic signaling pathway IMP
 biological_processGO:2000707 positive regulation of dense core granule biogenesis IMP
 cellular_componentGO:0001750 photoreceptor outer segment IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0035866 alphav-beta3 integrin-PKCalpha complex IDA
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0045177 apical part of cell IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0004697 protein kinase C activity ISO
 molecular_functionGO:0004698 calcium-dependent protein kinase C activity ISO
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0035403 histone kinase activity (H3-T6 specific) ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr