19106


Mus musculus (NCBI)

Features
Gene ID: 19106
  
Biological name :
  
Synonyms : 2310047A08Rik|4732414G15Rik|AI467567|AI747578|Pkr|Prkr|Tik / Eif2ak2 / eukaryotic translation initiation factor 2-alpha kinase 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422005_at (Mouse Genome 430 2.0 Array)   1422006_at (Mouse Genome 430 2.0 Array)   1440866_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6755160
RefSeq - XP_006523926.1
RefSeq - NC_000083.6
RefSeq - 568999442
RefSeq - NP_035293.1
RefSeq - NM_011163.4
RefSeq - XM_006523863.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000024079 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000186 activation of MAPKK activity ISO
 biological_processGO:0001819 positive regulation of cytokine production IMP
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006412 translation IDA
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009615 response to virus ISO
 biological_processGO:0009636 response to toxic substance ISO
 biological_processGO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0017148 negative regulation of translation ISO
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IDA
 biological_processGO:0032496 response to lipopolysaccharide ISO
 biological_processGO:0032722 positive regulation of chemokine production IMP
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IMP
 biological_processGO:0033197 response to vitamin E ISO
 biological_processGO:0033689 negative regulation of osteoblast proliferation ISO
 biological_processGO:0034198 cellular response to amino acid starvation ISO
 biological_processGO:0035455 response to interferon-alpha ISO
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043066 negative regulation of apoptotic process IGI
 biological_processGO:0045071 negative regulation of viral genome replication ISO
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:1900225 regulation of NLRP3 inflammasome complex assembly IMP
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IMP
 biological_processGO:1901532 regulation of hematopoietic progenitor cell differentiation IMP
 biological_processGO:1902033 regulation of hematopoietic stem cell proliferation IMP
 biological_processGO:1902036 regulation of hematopoietic stem cell differentiation IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0022626 cytosolic ribosome IBA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding ISO
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004694 eukaryotic translation initiation factor 2alpha kinase activity ISO
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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