19164


Mus musculus (NCBI)

Features
Gene ID: 19164
  
Biological name :
  
Synonyms : Ad3h|PS-1|PS1|S182 / presenilin 1 / Psen1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1420261_at (Mouse Genome 430 2.0 Array)   1421853_at (Mouse Genome 430 2.0 Array)   1425549_at (Mouse Genome 430 2.0 Array)   1450399_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1376175690
RefSeq - 568979086
RefSeq - 6679493
RefSeq - NC_000078.6
RefSeq - NP_001349200.1
RefSeq - NP_032969.1
RefSeq - XP_006515668.1
RefSeq - NM_001362271.1
RefSeq - NM_008943.2
RefSeq - XM_006515605.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000019969 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IMP
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0000186 activation of MAPKK activity IMP
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0001708 cell fate specification IGI
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0001921 positive regulation of receptor recycling IMP
 biological_processGO:0001933 negative regulation of protein phosphorylation IGI
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0001947 heart looping IGI
 biological_processGO:0002038 positive regulation of L-glutamate import across plasma membrane IMP
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IGI
 biological_processGO:0002265 astrocyte activation involved in immune response ISO
 biological_processGO:0002286 T cell activation involved in immune response IGI
 biological_processGO:0002573 myeloid leukocyte differentiation IGI
 biological_processGO:0006469 negative regulation of protein kinase activity IMP
 biological_processGO:0006486 protein glycosylation IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006509 membrane protein ectodomain proteolysis ISO
 biological_processGO:0006839 mitochondrial transport IMP
 biological_processGO:0006874 cellular calcium ion homeostasis IMP
 biological_processGO:0006914 autophagy IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0006979 response to oxidative stress IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007175 negative regulation of epidermal growth factor-activated receptor activity IMP
 biological_processGO:0007176 regulation of epidermal growth factor-activated receptor activity IGI
 biological_processGO:0007219 Notch signaling pathway IMP
 biological_processGO:0007220 Notch receptor processing IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007611 learning or memory ISO
 biological_processGO:0007613 memory TAS
 biological_processGO:0009791 post-embryonic development IMP
 biological_processGO:0015031 protein transport IGI
 biological_processGO:0015871 choline transport IMP
 biological_processGO:0016080 synaptic vesicle targeting IMP
 biological_processGO:0016485 protein processing ISO
 biological_processGO:0021795 cerebral cortex cell migration IMP
 biological_processGO:0021870 Cajal-Retzius cell differentiation IMP
 biological_processGO:0021904 dorsal/ventral neural tube patterning IGI
 biological_processGO:0021987 cerebral cortex development IMP
 biological_processGO:0022008 neurogenesis IMP
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0030326 embryonic limb morphogenesis IGI
 biological_processGO:0030900 forebrain development IGI
 biological_processGO:0032092 positive regulation of protein binding ISO
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis ISO
 biological_processGO:0033160 positive regulation of protein import into nucleus, translocation ISO
 biological_processGO:0034205 amyloid-beta formation ISO
 biological_processGO:0035282 segmentation IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0040011 locomotion IGI
 biological_processGO:0042325 regulation of phosphorylation ISO
 biological_processGO:0042327 positive regulation of phosphorylation ISO
 biological_processGO:0042982 amyloid precursor protein metabolic process ISO
 biological_processGO:0042987 amyloid precursor protein catabolic process IMP
 biological_processGO:0043011 myeloid dendritic cell differentiation IMP
 biological_processGO:0043065 positive regulation of apoptotic process IGI
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043085 positive regulation of catalytic activity ISO
 biological_processGO:0043393 regulation of protein binding IGI
 biological_processGO:0043406 positive regulation of MAP kinase activity IMP
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0043589 skin morphogenesis IMP
 biological_processGO:0044267 cellular protein metabolic process IMP
 biological_processGO:0045860 positive regulation of protein kinase activity IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0048143 astrocyte activation ISO
 biological_processGO:0048167 regulation of synaptic plasticity IMP
 biological_processGO:0048538 thymus development IMP
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0048705 skeletal system morphogenesis IMP
 biological_processGO:0048854 brain morphogenesis IGI
 biological_processGO:0050435 amyloid-beta metabolic process IMP
 biological_processGO:0050673 epithelial cell proliferation IGI
 biological_processGO:0050771 negative regulation of axonogenesis IMP
 biological_processGO:0050808 synapse organization ISO
 biological_processGO:0050820 positive regulation of coagulation IMP
 biological_processGO:0050852 T cell receptor signaling pathway IGI
 biological_processGO:0051402 neuron apoptotic process IGI
 biological_processGO:0051444 negative regulation of ubiquitin-protein transferase activity IMP
 biological_processGO:0051563 smooth endoplasmic reticulum calcium ion homeostasis IGI
 biological_processGO:0051604 protein maturation IGI
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IMP
 biological_processGO:0060070 canonical Wnt signaling pathway IBA
 biological_processGO:0060075 regulation of resting membrane potential IMP
 biological_processGO:0060291 long-term synaptic potentiation TAS
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IMP
 biological_processGO:0060999 positive regulation of dendritic spine development ISO
 biological_processGO:0090647 modulation of age-related behavioral decline ISO
 biological_processGO:0098609 cell-cell adhesion ISO
 biological_processGO:1904646 cellular response to amyloid-beta ISO
 biological_processGO:1904797 negative regulation of core promoter binding ISO
 biological_processGO:1905908 positive regulation of amyloid fibril formation ISO
 biological_processGO:1990535 neuron projection maintenance ISO
 biological_processGO:2000059 negative regulation of ubiquitin-dependent protein catabolic process IMP
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IGI
 cellular_componentGO:0000776 kinetochore ISO
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005640 nuclear outer membrane ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane ISO
 cellular_componentGO:0005765 lysosomal membrane ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005790 smooth endoplasmic reticulum ISO
 cellular_componentGO:0005791 rough endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0016235 aggresome ISO
 cellular_componentGO:0030054 cell junction ISO
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0030426 growth cone IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0031594 neuromuscular junction ISO
 cellular_componentGO:0031965 nuclear membrane ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0035253 ciliary rootlet IDA
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0043198 dendritic shaft IDA
 cellular_componentGO:0043227 membrane-bounded organelle IDA
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0070765 gamma-secretase complex ISO
 molecular_functionGO:0004175 endopeptidase activity ISO
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA
 molecular_functionGO:0005262 calcium channel activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding ISO
 molecular_functionGO:0008233 peptidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030165 PDZ domain binding ISO
 molecular_functionGO:0042500 aspartic endopeptidase activity, intramembrane cleaving ISO
 molecular_functionGO:0045296 cadherin binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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