19264


Mus musculus (NCBI)
cellregulationtsignalingpathwayproteinactivitydifferentiationbproliferationmediatedmembranebindingresponseadhesionimmunoglobulinstemreceptorplasmaphosphatasemapkcytotoxicityhematopoietichumoralimmunecirculatingkinasedephosphorylationmigrationcell-cell

Features
Gene ID: 19264
  
Biological name :
  
Synonyms : B220|CD45R|Cd45|L-CA|Ly-5|Lyt-4|T200|loc / protein tyrosine phosphatase, receptor type, C / Ptprc
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422124_a_at (Mouse Genome 430 2.0 Array)   1440165_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_006529325.1
RefSeq - 392871556
RefSeq - 392871558
RefSeq - 568908389
RefSeq - 568908391
RefSeq - 568908393
RefSeq - 568908395
RefSeq - 568908397
RefSeq - 568908399
RefSeq - NC_000067.6
RefSeq - NP_001104786.2
RefSeq - NP_001255215.1
RefSeq - NP_035340.3
RefSeq - XP_006529320.1
RefSeq - XP_006529321.1
RefSeq - XP_006529322.1
RefSeq - XP_006529323.1
RefSeq - XP_006529324.1
RefSeq - 392871554
RefSeq - NM_001111316.2
RefSeq - NM_001268286.1
RefSeq - NM_011210.4
RefSeq - XM_006529260.1
RefSeq - XM_006529261.3
RefSeq - XM_006529262.3
RefSeq - XM_006529257.1
RefSeq - XM_006529258.3
RefSeq - XM_006529259.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000026395 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processregulation of molecular functionorganic substance metabolic processcellular response to stimulusimmune responseleukocyte mediated cytotoxicityimmune effector processresponse to chemicalanatomical structure developmentcellular developmental processbiosynthetic processproduction of molecular mediator of immune responselocalization of cellmovement of cell or subcellular componentcell adhesionresponse to abiotic stimuluscell activationleukocyte proliferationcell cycleestablishment of localizationregulation of biological qualitycellular localizationresponse to stressresponse to external stimulusresponse to biotic stimulusstem cell proliferationcell deathnitrnitrogen compound metabolic processcellcell communicationcellcellular metabolic processprimprimary metabolic processreguregulation of molecular functionorgaorganic substance metabolic processcellcellular response to stimulusimmuimmune responseleukleukocyte mediated cytotoxicityimmuimmune effector processrespresponse to chemicalanatanatomical structure developmentcellcellular developmental processbiosbiosynthetic processprodproduction of molecular mediator of immune responselocalocalization of cellmovemovement of cell or subcellular componentcellcell adhesionrespresponse to abiotic stimuluscellcell activationleukleukocyte proliferationcellcell cycleestaestablishment of localizationreguregulation of biological qualitycellcellular localizationrespresponse to stressrespresponse to external stimulusrespresponse to biotic stimulusstemstem cell proliferationcellcell death
catalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, actcatalytic activity, acting on a proteinhydrolase activityhydrolase activityprotein bindingprotein bindingion bindingion bindingcarbohydrate derivativecarbohydrate derivative bindingsulfur compound bindingsulfur compound binding
cellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellcellmembranemembranecell junctioncell junction
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IMP
 biological_processGO:0001915 negative regulation of T cell mediated cytotoxicity IMP
 biological_processGO:0001916 positive regulation of T cell mediated cytotoxicity IMP
 biological_processGO:0001960 negative regulation of cytokine-mediated signaling pathway IDA
 biological_processGO:0002244 hematopoietic progenitor cell differentiation ISO
 biological_processGO:0002378 immunoglobulin biosynthetic process ISO
 biological_processGO:0002711 positive regulation of T cell mediated immunity IMP
 biological_processGO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin IMP
 biological_processGO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin IMP
 biological_processGO:0006469 negative regulation of protein kinase activity ISO
 biological_processGO:0006470 protein dephosphorylation IDA
 biological_processGO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration ISO
 biological_processGO:0007159 leukocyte cell-cell adhesion IMP
 biological_processGO:0010332 response to gamma radiation ISO
 biological_processGO:0016311 dephosphorylation IDA
 biological_processGO:0030183 B cell differentiation IMP
 biological_processGO:0030217 T cell differentiation IMP
 biological_processGO:0030890 positive regulation of B cell proliferation ISO
 biological_processGO:0031953 negative regulation of protein autophosphorylation IMP
 biological_processGO:0034113 heterotypic cell-cell adhesion IMP
 biological_processGO:0042098 T cell proliferation IMP
 biological_processGO:0042100 B cell proliferation IMP
 biological_processGO:0042102 positive regulation of T cell proliferation IMP
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0044770 cell cycle phase transition ISO
 biological_processGO:0045059 positive thymic T cell selection IMP
 biological_processGO:0045060 negative thymic T cell selection IMP
 biological_processGO:0045577 regulation of B cell differentiation IMP
 biological_processGO:0045582 positive regulation of T cell differentiation IMP
 biological_processGO:0045588 positive regulation of gamma-delta T cell differentiation IMP
 biological_processGO:0046641 positive regulation of alpha-beta T cell proliferation IMP
 biological_processGO:0048304 positive regulation of isotype switching to IgG isotypes IMP
 biological_processGO:0048539 bone marrow development ISO
 biological_processGO:0048864 stem cell development ISO
 biological_processGO:0050732 negative regulation of peptidyl-tyrosine phosphorylation IMP
 biological_processGO:0050852 T cell receptor signaling pathway ISO
 biological_processGO:0050853 B cell receptor signaling pathway IMP
 biological_processGO:0050855 regulation of B cell receptor signaling pathway IMP
 biological_processGO:0050857 positive regulation of antigen receptor-mediated signaling pathway IMP
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IDA
 biological_processGO:0051607 defense response to virus IMP
 biological_processGO:0051726 regulation of cell cycle IDA
 biological_processGO:2000473 positive regulation of hematopoietic stem cell migration ISO
 biological_processGO:2000648 positive regulation of stem cell proliferation ISO
 biological_processGO:2001236 regulation of extrinsic apoptotic signaling pathway IMP
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0071944 cell periphery IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0043395 heparan sulfate proteoglycan binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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