1958


Homo sapiens (NCBI)
regulationbindingtranscriptionresponsernapolymeraseiidnaprocesssequence-specificcellsignalingpathwaybiosyntheticcellularactivityinterleukin-hypoxiadifferentiationproteinpromoterglomerularmesangialproliferationregulatoryregionfactordna-bindingischemiaglucose

Features
Gene ID: 1958
  
Biological name :
  
Synonyms : AT225|G0S30|KROX-24|NGFI-A|TIS8|ZIF-268|ZNF225 / early growth response 1 / EGR1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 201693_s_at (Human Genome U133 Plus 2.0 Array)   201694_s_at (Human Genome U133 Plus 2.0 Array)   227404_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4503493
RefSeq - NC_000005.10
RefSeq - NG_021374.1
RefSeq - NP_001955.1
RefSeq - NM_001964.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000120738 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressresponse to abiotic stimulusresponse to chemicalanatomical structure developmentcellular developmental processcell activationcell communicationresponse to endogenous stimuluscellular response to stimuluscell deathmulticellular organism reproductioncytokine productionregulation of biological qualityimmune responseregulation of molecular functionsmall molecule metabolic processnitrognitrogen compound metabolic processbiosynbiosynthetic processcellulcellular metabolic processprimarprimary metabolic processorganiorganic substance metabolic processresponresponse to stressresponresponse to abiotic stimulusresponresponse to chemicalanatomanatomical structure developmentcellulcellular developmental processcell acell activationcell ccell communicationresponresponse to endogenous stimuluscellulcellular response to stimuluscell dcell deathmulticmulticellular organism reproductioncytokicytokine productionregularegulation of biological qualityimmuneimmune responseregularegulation of molecular functionsmall small molecule metabolic process
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingion bindingchromatin bindingorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingDNA-binding transcriptiDNA-binding transcription factor activityprotein bindingprotein bindingion bindingion bindingchromatin bindingchromatin binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001666 response to hypoxia ISS
 biological_processGO:0002931 response to ischemia ISS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II IDA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0030217 T cell differentiation IEA
 biological_processGO:0030509 BMP signaling pathway IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0033233 regulation of protein sumoylation IDA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0044849 estrous cycle ISS
 biological_processGO:0045080 positive regulation of chemokine biosynthetic process ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0046886 positive regulation of hormone biosynthetic process ISS
 biological_processGO:0050725 positive regulation of interleukin-1 beta biosynthetic process ISS
 biological_processGO:0060337 type I interferon signaling pathway TAS
 biological_processGO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia IEA
 biological_processGO:0070498 interleukin-1-mediated signaling pathway IMP
 biological_processGO:0071480 cellular response to gamma radiation IEA
 biological_processGO:0071504 cellular response to heparin ISS
 biological_processGO:0071506 cellular response to mycophenolic acid ISS
 biological_processGO:0072110 glomerular mesangial cell proliferation ISS
 biological_processGO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation ISS
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0098759 cellular response to interleukin-8 IDA
 biological_processGO:1901216 positive regulation of neuron death ISS
 biological_processGO:1902949 positive regulation of tau-protein kinase activity ISS
 biological_processGO:2000182 regulation of progesterone biosynthetic process ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0010385 double-stranded methylated DNA binding IDA
 molecular_functionGO:0035035 histone acetyltransferase binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044729 hemi-methylated DNA-binding IDA
 molecular_functionGO:1990841 promoter-specific chromatin binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr