1965


Homo sapiens (NCBI)

Features
Gene ID: 1965
  
Biological name :
  
Synonyms : EIF-2|EIF-2A|EIF-2alpha|EIF2|EIF2A / EIF2S1 / eukaryotic translation initiation factor 2 subunit alpha
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 201142_at (Human Genome U133 Plus 2.0 Array)   201143_s_at (Human Genome U133 Plus 2.0 Array)   201144_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4758256
RefSeq - NC_000014.9
RefSeq - NP_004085.1
RefSeq - NM_004094.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000134001 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0032057 negative regulation of translational initiation in response to stress ISS
 biological_processGO:0034063 stress granule assembly ISS
 biological_processGO:0034198 cellular response to amino acid starvation ISS
 biological_processGO:0034599 cellular response to oxidative stress ISS
 biological_processGO:0034605 cellular response to heat IEA
 biological_processGO:0034644 cellular response to UV ISS
 biological_processGO:0034976 response to endoplasmic reticulum stress ISS
 biological_processGO:0036499 PERK-mediated unfolded protein response NAS
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0055085 transmembrane transport TAS
 biological_processGO:1901216 positive regulation of neuron death IMP
 biological_processGO:1905098 negative regulation of guanyl-nucleotide exchange factor activity IEA
 biological_processGO:1990737 response to manganese-induced endoplasmic reticulum stress IEA
 biological_processGO:2000676 positive regulation of type B pancreatic cell apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005844 polysome TAS
 cellular_componentGO:0005850 eukaryotic translation initiation factor 2 complex IDA
 cellular_componentGO:0005851 eukaryotic translation initiation factor 2B complex IDA
 cellular_componentGO:0010494 cytoplasmic stress granule ISS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IBA
 cellular_componentGO:0043614 multi-eIF complex IBA
 cellular_componentGO:0044207 translation initiation ternary complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097451 glial limiting end-foot IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003743 translation initiation factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043022 ribosome binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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