19877


Mus musculus (NCBI)

Features
Gene ID: 19877
  
Biological name :
  
Synonyms : 1110055K06Rik|Rock-I / Rho-associated coiled-coil containing protein kinase 1 / Rock1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1423444_at (Mouse Genome 430 2.0 Array)   1423445_at (Mouse Genome 430 2.0 Array)   1441162_at (Mouse Genome 430 2.0 Array)   1450994_at (Mouse Genome 430 2.0 Array)   1460729_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 569003431
RefSeq - 6677759
RefSeq - NC_000084.6
RefSeq - NP_033097.1
RefSeq - XP_006525788.1
RefSeq - XM_006525725.1
RefSeq - NM_009071.2
RefSeq - XR_001782350.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000024290 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003383 apical constriction IGI
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007010 cytoskeleton organization ISO
 biological_processGO:0007159 leukocyte cell-cell adhesion ISO
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0007266 Rho protein signal transduction ISO
 biological_processGO:0010508 positive regulation of autophagy ISO
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016525 negative regulation of angiogenesis ISO
 biological_processGO:0022614 membrane to membrane docking ISO
 biological_processGO:0030036 actin cytoskeleton organization IGI
 biological_processGO:0030866 cortical actin cytoskeleton organization ISO
 biological_processGO:0031175 neuron projection development ISO
 biological_processGO:0032060 bleb assembly IMP
 biological_processGO:0032091 negative regulation of protein binding ISO
 biological_processGO:0032956 regulation of actin cytoskeleton organization ISO
 biological_processGO:0032970 regulation of actin filament-based process IGI
 biological_processGO:0035509 negative regulation of myosin-light-chain-phosphatase activity ISO
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0045616 regulation of keratinocyte differentiation ISO
 biological_processGO:0045664 regulation of neuron differentiation ISO
 biological_processGO:0050900 leukocyte migration ISO
 biological_processGO:0050901 leukocyte tethering or rolling ISO
 biological_processGO:0051451 myoblast migration IMP
 biological_processGO:0051492 regulation of stress fiber assembly IEA
 biological_processGO:0051493 regulation of cytoskeleton organization IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IMP
 biological_processGO:0071559 response to transforming growth factor beta IGI
 biological_processGO:0072659 protein localization to plasma membrane ISO
 biological_processGO:0110061 regulation of angiotensin-activated signaling pathway ISO
 biological_processGO:0140058 neuron projection arborization ISO
 biological_processGO:1900223 positive regulation of amyloid-beta clearance ISO
 biological_processGO:1900242 regulation of synaptic vesicle endocytosis ISO
 biological_processGO:1902430 negative regulation of amyloid-beta formation ISO
 biological_processGO:1902992 negative regulation of amyloid precursor protein catabolic process ISO
 biological_processGO:1903140 regulation of establishment of endothelial barrier ISO
 biological_processGO:1903347 negative regulation of bicellular tight junction assembly ISO
 biological_processGO:1905205 positive regulation of connective tissue replacement ISO
 biological_processGO:1990776 response to angiotensin IGI
 biological_processGO:2000114 regulation of establishment of cell polarity IEA
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005856 cytoskeleton IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0010494 cytoplasmic stress granule IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0106003 amyloid-beta complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA
 molecular_functionGO:0017049 GTP-Rho binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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