19878


Mus musculus (NCBI)

Features
Gene ID: 19878
  
Biological name :
  
Synonyms : B230113H15Rik|ROKalpha|Rho-kinase|Rock-II|Rock2m|mKIAA0619 / Rho-associated coiled-coil containing protein kinase 2 / Rock2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1423592_at (Mouse Genome 430 2.0 Array)   1451041_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_006515083.1
RefSeq - 568977599
RefSeq - 568977601
RefSeq - NC_000078.6
RefSeq - NP_033098.2
RefSeq - XP_006515082.1
RefSeq - 134949013
RefSeq - NM_009072.2
RefSeq - XM_006515020.3
RefSeq - XM_006515019.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000020580 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001843 neural tube closure IGI
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006939 smooth muscle contraction IEA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0007266 Rho protein signal transduction ISO
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IGI
 biological_processGO:0010595 positive regulation of endothelial cell migration ISO
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy IMP
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010825 positive regulation of centrosome duplication IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016525 negative regulation of angiogenesis ISO
 biological_processGO:0018105 peptidyl-serine phosphorylation ISO
 biological_processGO:0018107 peptidyl-threonine phosphorylation ISO
 biological_processGO:0030036 actin cytoskeleton organization IGI
 biological_processGO:0030866 cortical actin cytoskeleton organization ISO
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0035509 negative regulation of myosin-light-chain-phosphatase activity ISO
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0039694 viral RNA genome replication ISO
 biological_processGO:0042752 regulation of circadian rhythm IMP
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0045616 regulation of keratinocyte differentiation ISO
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0048813 dendrite morphogenesis IGI
 biological_processGO:0051246 regulation of protein metabolic process IMP
 biological_processGO:0051298 centrosome duplication ISO
 biological_processGO:0071394 cellular response to testosterone stimulus ISO
 biological_processGO:0071559 response to transforming growth factor beta IGI
 biological_processGO:0072659 protein localization to plasma membrane ISO
 biological_processGO:0110061 regulation of angiotensin-activated signaling pathway IMP
 biological_processGO:0150033 negative regulation of protein localization to lysosome ISO
 biological_processGO:1902004 positive regulation of amyloid-beta formation ISO
 biological_processGO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process ISO
 biological_processGO:1902966 positive regulation of protein localization to early endosome ISO
 biological_processGO:1902993 positive regulation of amyloid precursor protein catabolic process ISO
 biological_processGO:1903140 regulation of establishment of endothelial barrier ISO
 biological_processGO:1903347 negative regulation of bicellular tight junction assembly ISO
 biological_processGO:1905205 positive regulation of connective tissue replacement IMP
 biological_processGO:1990776 response to angiotensin IGI
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031616 spindle pole centrosome IDA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0072518 Rho-dependent protein serine/threonine kinase activity ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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