20304


Mus musculus (NCBI)
regulationcellresponseactivitychemotaxisreceptorproteinsignalingchemokinebindingcellulartcell-celladhesionpathwayprocessccrcalciumionmigrationactivationphospholipaseproliferationkinaseneurondeathapoptoticcascadevirushost

Features
Gene ID: 20304
  
Biological name :
  
Synonyms : Ccl5 / chemokine (C-C motif) ligand 5 / MuRantes|RANTES|SISd|Scya5|TCP228
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1418126_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 164698428
RefSeq - NC_000077.6
RefSeq - NP_038681.2
RefSeq - NM_013653.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000035042 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to stressresponse to external stimulusresponse to biotic stimulusimmune effector processresponse to chemicallocalization of cellmovement of cell or subcellular componentestablishment of localizationregulation of biological qualityimmune responsecell adhesioncellular component organizationcellular component biogenesisbiosynthetic processregulation of molecular functioncell activationleukocyte proliferationinterspecies interaction between organismsanatomical structure developmentcellular developmental processmuscle cell proliferationepithelial cell proliferationmacromolecule localizationcell deathcytokine productionnitrnitrogen compound metabolic processcellcell communicationcellcellular metabolic processprimprimary metabolic processorgaorganic substance metabolic processcellcellular response to stimulusrespresponse to stressrespresponse to external stimulusrespresponse to biotic stimulusimmuimmune effector processrespresponse to chemicallocalocalization of cellmovemovement of cell or subcellular componentestaestablishment of localizationreguregulation of biological qualityimmuimmune responsecellcell adhesioncellcellular component organizationcellcellular component biogenesisbiosbiosynthetic processreguregulation of molecular functioncellcell activationleukleukocyte proliferationinteinterspecies interaction between organismsanatanatomical structure developmentcellcellular developmental processmuscmuscle cell proliferationepitepithelial cell proliferationmacrmacromolecule localizationcellcell deathcytocytokine production
hydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activitycatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingenzyme regulator activityhydrolase activhydrolase activitycatalytic activcatalytic activity, acting on a proteintransferase acttransferase activityprotein bindingprotein bindingreceptor regulareceptor regulator activityion bindingion bindingcarbohydrate decarbohydrate derivative bindingsulfur compoundsulfur compound bindingenzyme regulatoenzyme regulator activity
extracellular regioncellextracellular regioncellextracellular regioncellextracellular regioncellextracellular regioncellextracellular regioncellextracellular regioncellextracellular regioncellextracellular regioncellextracellular regioncellextracellular regionextracellular regioncellcell
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade ISO
 biological_processGO:0002230 positive regulation of defense response to virus by host IC
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006816 calcium ion transport ISO
 biological_processGO:0006874 cellular calcium ion homeostasis ISO
 biological_processGO:0006887 exocytosis ISO
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response ISO
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007159 leukocyte cell-cell adhesion ISO
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007267 cell-cell signaling ISO
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0009636 response to toxic substance ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010759 positive regulation of macrophage chemotaxis ISO
 biological_processGO:0010820 positive regulation of T cell chemotaxis ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0014911 positive regulation of smooth muscle cell migration ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0031269 pseudopodium assembly ISO
 biological_processGO:0031328 positive regulation of cellular biosynthetic process ISO
 biological_processGO:0031584 activation of phospholipase D activity ISO
 biological_processGO:0031622 positive regulation of fever generation ISO
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway ISO
 biological_processGO:0033634 positive regulation of cell-cell adhesion mediated by integrin ISO
 biological_processGO:0034097 response to cytokine IDA
 biological_processGO:0034112 positive regulation of homotypic cell-cell adhesion ISO
 biological_processGO:0034341 response to interferon-gamma ISO
 biological_processGO:0034612 response to tumor necrosis factor IDA
 biological_processGO:0035688 T-helper 1 cell diapedesis ISO
 biological_processGO:0042102 positive regulation of T cell proliferation ISO
 biological_processGO:0042119 neutrophil activation ISO
 biological_processGO:0042327 positive regulation of phosphorylation ISO
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISO
 biological_processGO:0043491 protein kinase B signaling ISO
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0043922 negative regulation by host of viral transcription ISO
 biological_processGO:0045071 negative regulation of viral genome replication ISO
 biological_processGO:0045666 positive regulation of neuron differentiation ISO
 biological_processGO:0045672 positive regulation of osteoclast differentiation ISO
 biological_processGO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0045785 positive regulation of cell adhesion ISO
 biological_processGO:0048245 eosinophil chemotaxis ISO
 biological_processGO:0048247 lymphocyte chemotaxis ISO
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IMP
 biological_processGO:0050796 regulation of insulin secretion ISO
 biological_processGO:0050863 regulation of T cell activation ISO
 biological_processGO:0051262 protein tetramerization ISO
 biological_processGO:0051928 positive regulation of calcium ion transport ISO
 biological_processGO:0060548 negative regulation of cell death ISO
 biological_processGO:0060754 positive regulation of mast cell chemotaxis ISO
 biological_processGO:0070098 chemokine-mediated signaling pathway ISO
 biological_processGO:0070233 negative regulation of T cell apoptotic process ISO
 biological_processGO:0070234 positive regulation of T cell apoptotic process ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:0071407 cellular response to organic cyclic compound ISO
 biological_processGO:0090026 positive regulation of monocyte chemotaxis ISO
 biological_processGO:1901214 regulation of neuron death ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:2000110 negative regulation of macrophage apoptotic process IMP
 biological_processGO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production NAS
 biological_processGO:2000406 positive regulation of T cell migration ISO
 biological_processGO:2000503 positive regulation of natural killer cell chemotaxis ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity ISO
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity ISO
 molecular_functionGO:0008201 heparin binding ISO
 molecular_functionGO:0016004 phospholipase activator activity ISO
 molecular_functionGO:0030298 receptor signaling protein tyrosine kinase activator activity ISO
 molecular_functionGO:0031726 CCR1 chemokine receptor binding ISO
 molecular_functionGO:0031729 CCR4 chemokine receptor binding IEA
 molecular_functionGO:0031730 CCR5 chemokine receptor binding ISO
 molecular_functionGO:0042056 chemoattractant activity ISO
 molecular_functionGO:0042379 chemokine receptor binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043621 protein self-association ISO
 molecular_functionGO:0046817 chemokine receptor antagonist activity ISO
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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