2046


Homo sapiens (NCBI)
regulationkinaseactivityreceptorcellproteinadhesionneuronmembranedevelopmentprojectioncascadeephrinsignalingerkplasmatyrosinetransmembranebindingsubstrate-dependentmigrationmulticellularorganismaxonguidancesignaltransductionremodelingpeptidyl-tyrosinephosphorylation

Features
Gene ID: 2046
  
Biological name :
  
Synonyms : EEK|EK3|HEK3 / EPHA8 / EPH receptor A8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554069_at (Human Genome U133 Plus 2.0 Array)   231796_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767903068
RefSeq - NC_000001.11
RefSeq - XP_011539271.1
RefSeq - XP_011539272.1
RefSeq - XP_011539274.1
RefSeq - XP_011539275.1
RefSeq - XP_011539277.1
RefSeq - XP_024309660.1
RefSeq - 10140845
RefSeq - 1370452247
RefSeq - 55770892
RefSeq - NP_001006944.1
RefSeq - NP_065387.1
RefSeq - 767903053
RefSeq - 767903055
RefSeq - 767903059
RefSeq - 767903061
RefSeq - XR_946576.2
RefSeq - NM_001006943.2
RefSeq - NM_020526.4
RefSeq - XM_011540969.1
RefSeq - XM_011540970.1
RefSeq - XM_011540972.1
RefSeq - XM_011540973.1
RefSeq - XM_011540975.3
RefSeq - XM_024453892.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000070886 to get all the annotations available for this gene.


Gene Ontology (GO)
localization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalization of cellmovement of cell or subcellular componentcell adhesionanatomical structure developmentresponse to external stimuluscellular component organizationresponse to chemicalcellular developmental processcell communicationcellular response to stimulusdevelopmental maturationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell deathresponse to endogenous stimuluslocalizlocalization of cellmovemenmovement of cell or subcellular componentcell adcell adhesionanatomianatomical structure developmentresponsresponse to external stimuluscellulacellular component organizationresponsresponse to chemicalcellulacellular developmental processcell cocell communicationcellulacellular response to stimulusdevelopdevelopmental maturationnitrogenitrogen compound metabolic processcellulacellular metabolic processprimaryprimary metabolic processorganicorganic substance metabolic processregulatregulation of molecular functioncell decell deathresponsresponse to endogenous stimulus
catalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingprotein bindingcatalytic acticatalytic activity, acting on a proteintransferase actransferase activitysignaling recesignaling receptor activityion bindingion bindingcarbohydrate dcarbohydrate derivative bindingorganic cyclicorganic cyclic compound bindingheterocyclic cheterocyclic compound bindingsmall moleculesmall molecule bindingdrug bindingdrug bindingprotein bindinprotein binding
cellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellcellmembranemembraneorganelleorganelleprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006929 substrate-dependent cell migration ISS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007411 axon guidance ISS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0016322 neuron remodeling ISS
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030155 regulation of cell adhesion ISS
 biological_processGO:0031175 neuron projection development ISS
 biological_processGO:0033628 regulation of cell adhesion mediated by integrin ISS
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade ISS
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity ISS
 biological_processGO:0046777 protein autophosphorylation ISS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071372 cellular response to follicle-stimulating hormone stimulus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005004 GPI-linked ephrin receptor activity ISS
 molecular_functionGO:0005005 transmembrane-ephrin receptor activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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