2068


Homo sapiens (NCBI)

Features
Gene ID: 2068
  
Biological name :
  
Synonyms : COFS2|EM9|TFIIH|TTD|TTD1|XPD / ERCC2 / ERCC excision repair 2, TFIIH core complex helicase subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 213468_at (Human Genome U133 Plus 2.0 Array)   235399_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034606756
RefSeq - 15834617
RefSeq - 195947407
RefSeq - 768007305
RefSeq - NC_000019.10
RefSeq - NG_007067.2
RefSeq - NP_000391.1
RefSeq - NP_001124339.1
RefSeq - XP_011524913.1
RefSeq - XP_016881956.1
RefSeq - XM_011526611.2
RefSeq - XM_017026467.1
RefSeq - NM_000400.3
RefSeq - NM_001130867.1
RefSeq - XR_001753633.2
RefSeq - XR_001753634.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000104884 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000019 regulation of mitotic recombination IBA
 biological_processGO:0000717 nucleotide-excision repair, DNA duplex unwinding IBA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair TAS
 biological_processGO:0006289 nucleotide-excision repair NAS
 biological_processGO:0006293 nucleotide-excision repair, preincision complex stabilization TAS
 biological_processGO:0006294 nucleotide-excision repair, preincision complex assembly TAS
 biological_processGO:0006296 nucleotide-excision repair, DNA incision, 5"-to lesion TAS
 biological_processGO:0006361 transcription initiation from RNA polymerase I promoter TAS
 biological_processGO:0006363 termination of RNA polymerase I transcription TAS
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0006370 7-methylguanosine mRNA capping TAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0006979 response to oxidative stress IMP
 biological_processGO:0007059 chromosome segregation IMP
 biological_processGO:0007568 aging IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0009411 response to UV IBA
 biological_processGO:0009650 UV protection IGI
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0030282 bone mineralization IEA
 biological_processGO:0032289 central nervous system myelin formation IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0033683 nucleotide-excision repair, DNA incision TAS
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0035315 hair cell differentiation IMP
 biological_processGO:0040016 embryonic cleavage IEA
 biological_processGO:0043249 erythrocyte maturation IEA
 biological_processGO:0043388 positive regulation of DNA binding IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0045951 positive regulation of mitotic recombination IBA
 biological_processGO:0048568 embryonic organ development IEA
 biological_processGO:0048820 hair follicle maturation IEA
 biological_processGO:0060218 hematopoietic stem cell differentiation IEA
 biological_processGO:0070911 global genome nucleotide-excision repair TAS
 biological_processGO:1901990 regulation of mitotic cell cycle phase transition IMP
 cellular_componentGO:0000439 core TFIIH complex IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005669 transcription factor TFIID complex IDA
 cellular_componentGO:0005675 holo TFIIH complex TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005819 spindle IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex IDA
 cellular_componentGO:0071817 MMXD complex IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0008094 DNA-dependent ATPase activity TAS
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IDA
 molecular_functionGO:0043139 5"-3" DNA helicase activity IDA
 molecular_functionGO:0043141 ATP-dependent 5"-3" DNA helicase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IPI
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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