2099


Homo sapiens (NCBI)

Features
Gene ID: 2099
  
Biological name :
  
Synonyms : ER|ESR|ESRA|ESTRR|Era|NR3A1 / ESR1 / estrogen receptor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205225_at (Human Genome U133 Plus 2.0 Array)   211233_x_at (Human Genome U133 Plus 2.0 Array)   211234_x_at (Human Genome U133 Plus 2.0 Array)   211235_s_at (Human Genome U133 Plus 2.0 Array)   211627_x_at (Human Genome U133 Plus 2.0 Array)   215551_at (Human Genome U133 Plus 2.0 Array)   215552_s_at (Human Genome U133 Plus 2.0 Array)   217163_at (Human Genome U133 Plus 2.0 Array)   217190_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 62821794
RefSeq - 1034648821
RefSeq - 1034648823
RefSeq - 1034648825
RefSeq - 1034648827
RefSeq - 1034648829
RefSeq - 1034648832
RefSeq - 1034648838
RefSeq - 1034648843
RefSeq - 170295800
RefSeq - 170295802
RefSeq - 170295804
RefSeq - 578812488
RefSeq - 578812490
RefSeq - 601984548
RefSeq - 602617469
RefSeq - 1034542394
RefSeq - 767942150
RefSeq - 767942152
RefSeq - 767942154
RefSeq - 767942158
RefSeq - 767942164
RefSeq - NC_000006.12
RefSeq - NG_008493.2
RefSeq - NP_000116.2
RefSeq - NP_001116212.1
RefSeq - NP_001116213.1
RefSeq - NP_001116214.1
RefSeq - NP_001278159.1
RefSeq - NP_001278170.1
RefSeq - NP_001315029.1
RefSeq - XP_006715437.1
RefSeq - XP_006715438.1
RefSeq - XP_011533845.1
RefSeq - XP_011533846.1
RefSeq - XP_011533847.1
RefSeq - XP_011533849.1
RefSeq - XP_011533851.1
RefSeq - XP_016865865.1
RefSeq - XP_016865866.1
RefSeq - XP_016865867.1
RefSeq - XP_016865868.1
RefSeq - XP_016865869.1
RefSeq - XP_016865870.1
RefSeq - XP_016865871.1
RefSeq - XP_016865872.1
RefSeq - XM_017010377.1
RefSeq - XM_017010378.1
RefSeq - NM_000125.3
RefSeq - NM_001122740.1
RefSeq - NM_001122741.1
RefSeq - NM_001122742.1
RefSeq - NM_001291230.1
RefSeq - NM_001291241.1
RefSeq - NM_001328100.1
RefSeq - XM_017010379.1
RefSeq - XM_017010380.1
RefSeq - XM_017010381.1
RefSeq - XM_017010382.2
RefSeq - XM_017010383.1
RefSeq - XR_002956266.1
RefSeq - XR_001743223.2
RefSeq - XM_006715374.3
RefSeq - XM_006715375.3
RefSeq - XM_011535543.2
RefSeq - XM_011535544.2
RefSeq - XM_011535545.2
RefSeq - XM_011535547.2
RefSeq - XM_011535549.2
RefSeq - XM_017010376.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000091831 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001547 antral ovarian follicle growth IEA
 biological_processGO:0002064 epithelial cell development IEA
 biological_processGO:0006338 chromatin remodeling NAS
 biological_processGO:0006351 transcription, DNA-templated TAS
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006366 transcription by RNA polymerase II IDA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway ISS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration ISS
 biological_processGO:0008209 androgen metabolic process IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0010863 positive regulation of phospholipase C activity ISS
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030111 regulation of Wnt signaling pathway TAS
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway ISS
 biological_processGO:0030520 intracellular estrogen receptor signaling pathway NAS
 biological_processGO:0032355 response to estradiol IDA
 biological_processGO:0033146 regulation of intracellular estrogen receptor signaling pathway TAS
 biological_processGO:0034121 regulation of toll-like receptor signaling pathway IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0043627 response to estrogen IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 biological_processGO:0048863 stem cell differentiation IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060065 uterus development IEA
 biological_processGO:0060068 vagina development IEA
 biological_processGO:0060523 prostate epithelial cord elongation IEA
 biological_processGO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis IEA
 biological_processGO:0060687 regulation of branching involved in prostate gland morphogenesis IEA
 biological_processGO:0060745 mammary gland branching involved in pregnancy IEA
 biological_processGO:0060749 mammary gland alveolus development IEA
 biological_processGO:0060750 epithelial cell proliferation involved in mammary gland duct elongation IEA
 biological_processGO:0071168 protein localization to chromatin IMP
 biological_processGO:0071391 cellular response to estrogen stimulus IEA
 biological_processGO:0071392 cellular response to estradiol stimulus ISS
 biological_processGO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA IMP
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0035327 transcriptionally active chromatin IDA
 cellular_componentGO:0097550 transcriptional preinitiation complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001093 TFIIB-class transcription factor binding IPI
 molecular_functionGO:0001223 transcription coactivator binding IPI
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0003707 steroid hormone receptor activity TAS
 molecular_functionGO:0005496 steroid binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0017025 TBP-class protein binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0030235 nitric-oxide synthase regulator activity NAS
 molecular_functionGO:0030284 estrogen receptor activity TAS
 molecular_functionGO:0030331 estrogen receptor binding IPI
 molecular_functionGO:0034056 estrogen response element binding IDA
 molecular_functionGO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding IGI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0051117 ATPase binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr