2146


Homo sapiens (NCBI)

Features
Gene ID: 2146
  
Biological name :
  
Synonyms : enhancer of zeste 2 polycomb repressive complex 2 subunit / ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 / EZH2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203358_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767947055
RefSeq - 1034654393
RefSeq - 1034654401
RefSeq - 1034654404
RefSeq - 1034654410
RefSeq - 1370509647
RefSeq - 21361095
RefSeq - 23510384
RefSeq - 322506097
RefSeq - 322506099
RefSeq - 322506101
RefSeq - 530386930
RefSeq - 530386932
RefSeq - 530386934
RefSeq - 767947033
RefSeq - 767947036
RefSeq - 767947038
RefSeq - 767947041
RefSeq - 767947043
RefSeq - 767947045
RefSeq - 767947047
RefSeq - 767947049
RefSeq - 767947051
RefSeq - 767947053
RefSeq - 1034654383
RefSeq - 767947057
RefSeq - 767947059
RefSeq - 767947062
RefSeq - 767947064
RefSeq - 767947066
RefSeq - 767947068
RefSeq - 767947072
RefSeq - NC_000007.14
RefSeq - NG_032043.1
RefSeq - NP_001190176.1
RefSeq - NP_001190177.1
RefSeq - NP_001190178.1
RefSeq - NP_004447.2
RefSeq - NP_694543.1
RefSeq - XP_005250019.1
RefSeq - XP_005250020.1
RefSeq - XP_005250021.1
RefSeq - XP_011514185.1
RefSeq - XP_011514186.1
RefSeq - XP_011514187.1
RefSeq - XP_011514188.1
RefSeq - XP_011514189.1
RefSeq - XP_011514190.1
RefSeq - XP_011514191.1
RefSeq - XP_011514192.1
RefSeq - XP_011514193.1
RefSeq - XP_011514194.1
RefSeq - XP_011514195.1
RefSeq - XP_011514196.1
RefSeq - XP_011514197.1
RefSeq - XP_011514198.1
RefSeq - XP_011514199.1
RefSeq - XP_011514200.1
RefSeq - XP_011514201.1
RefSeq - XP_011514203.1
RefSeq - XP_016867306.1
RefSeq - XP_016867307.1
RefSeq - XP_016867308.1
RefSeq - XP_016867309.1
RefSeq - XP_016867310.1
RefSeq - XP_024302448.1
RefSeq - XM_017011818.1
RefSeq - XM_017011819.1
RefSeq - XM_017011820.2
RefSeq - NM_001203247.1
RefSeq - NM_001203248.1
RefSeq - NM_001203249.1
RefSeq - NM_004456.4
RefSeq - NM_152998.2
RefSeq - XM_017011821.1
RefSeq - XM_024446680.1
RefSeq - XR_001744581.1
RefSeq - XR_002956413.1
RefSeq - XR_002956414.1
RefSeq - XM_005249962.4
RefSeq - XM_005249963.4
RefSeq - XM_005249964.4
RefSeq - XM_011515883.2
RefSeq - XM_011515884.2
RefSeq - XM_011515885.2
RefSeq - XM_011515886.2
RefSeq - XM_011515887.3
RefSeq - XM_011515888.2
RefSeq - XM_011515889.2
RefSeq - XM_011515890.2
RefSeq - XM_011515891.3
RefSeq - XM_011515892.2
RefSeq - XM_011515893.2
RefSeq - XM_011515894.2
RefSeq - XM_011515895.2
RefSeq - XM_011515896.2
RefSeq - XM_011515897.2
RefSeq - XM_011515898.2
RefSeq - XM_011515899.3
RefSeq - XM_011515901.3
RefSeq - XM_017011817.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000106462 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006306 DNA methylation IEA
 biological_processGO:0006325 chromatin organization TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated TAS
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IDA
 biological_processGO:0014013 regulation of gliogenesis IEA
 biological_processGO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration IEA
 biological_processGO:0014898 cardiac muscle hypertrophy in response to stress IEA
 biological_processGO:0016571 histone methylation IMP
 biological_processGO:0021695 cerebellar cortex development IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0035984 cellular response to trichostatin A IEA
 biological_processGO:0036333 hepatocyte homeostasis IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042752 regulation of circadian rhythm IMP
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0045605 negative regulation of epidermal cell differentiation IEA
 biological_processGO:0045814 negative regulation of gene expression, epigenetic TAS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0048387 negative regulation of retinoic acid receptor signaling pathway IMP
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0051154 negative regulation of striated muscle cell differentiation IEA
 biological_processGO:0070301 cellular response to hydrogen peroxide IEA
 biological_processGO:0070314 G1 to G0 transition IEA
 biological_processGO:0070317 negative regulation of G0 to G1 transition TAS
 biological_processGO:0070734 histone H3-K27 methylation IDA
 biological_processGO:0071168 protein localization to chromatin IEA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IDA
 biological_processGO:0097421 liver regeneration IEA
 biological_processGO:0098532 histone H3-K27 trimethylation IEA
 biological_processGO:1900006 positive regulation of dendrite development IEA
 biological_processGO:1904772 response to tetrachloromethane IEA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0035098 ESC/E(Z) complex IDA
 cellular_componentGO:0045120 pronucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISS
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016279 protein-lysine N-methyltransferase activity TAS
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity TAS
 molecular_functionGO:0031490 chromatin DNA binding IDA
 molecular_functionGO:0042054 histone methyltransferase activity IMP
 molecular_functionGO:0043021 ribonucleoprotein complex binding IEA
 molecular_functionGO:0046976 histone methyltransferase activity (H3-K27 specific) TAS
 molecular_functionGO:0070878 primary miRNA binding IEA
 molecular_functionGO:1990841 promoter-specific chromatin binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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